IP Library › Granted Patent US 8,185,485
Granted Patent B2
US 8,185,485 · App. 12/198,967 · Granted May 22, 2012

Device for analyzing thermal data based on breast surface temperature for the detection for use in determining cancerous conditions

Assignee: Lifeline Biotechnologies, Inc.
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Quick Facts
Patent No.
US 8,185,485
App. No.
12/198,967
Granted
May 22, 2012
Kind
B2
Abstract

A device for providing improved classification of breast tissue wherein the tissue is classified as one of cancerous and non-cancerous tissue includes sensors for sensing temperature of a subject breast tissue over a predetermined period and generating signals in response thereto and a computer operatively connected to the sensors for receiving and manipulating the signals operatively associated with a normalizer for applying a normalization to each the signal by a function of X/Y where X is one temperature reading of one of the signals for a particular subject and Y is the maximum temperature obtained from a predetermined number sets of temperature readings obtained a plurality of subject breast tissue from the subject to provide a set of normalized signals used by a trained artificial classifier to produce a signal indicative of cancerous and non-cancerous tissue of the subject.

Claims (12)

1. A device for providing improved classification of breast tissue wherein the tissue: is classified as one of cancerous and non-cancerous tissue, which comprises:

means for sensing temperature of a subject breast tissue over a predetermined period and generating signals in response thereto;

means operatively associated with said means for sensing for receiving and manipulating said signals employing a computer based device operatively associated with means for applying a normalization to each said signal, said normalization including a function of X/Y where X is one temperature reading of one of said signals for a particular subject and Y is the maximum temperature obtained from a predetermined number sets of temperature readings obtained a plurality of subject breast tissue from said subject, said normalization to provide a set of normalized signals and said computer based device operatively associated with a trained artificial classifier and wherein said set normalized signals are input through said trained artificial classifier to produce a signal indicative of cancerous and non-cancerous tissue of the subject.

2. The device for providing improved classification of breast tissue of claim 1 , wherein said computer based device is operatively associated with a plurality of trained artificial classifiers and wherein said set normalized signals are input through said trained artificial classifiers to produce signals indicative of cancerous and non-cancerous tissue of the subject.

3. The device for providing improved classification of breast tissue of claim 1 , wherein said classifier is further trained using said normalized signals.

4. The device for providing improved classification of breast tissue of claim 2 , wherein said classifiers are selected from a group of Back-Propagation, Radial Basis Function, Gaussian Mixture Model, Fuzzy Network and Support Vector Machine.

5. A method for providing improved classification of breast tissue wherein the tissue is classified as one of cancerous and non-cancerous tissue, which comprises:

(a) sensing temperature of a subject breast tissue over a predetermined period and generating signals in response thereto;

(b) employing a computer based device having means for receiving and manipulating said signals, applying a normalization to each said signal, said normalization including a function of X/Y where X is one temperature reading of a given set of readings for a particular subject and Y is the maximum temperature obtained from a predetermined number sets of temperature readings obtained a plurality of subject breast tissue from said subject, said normalization to provide a set of normalized signals and said computer based device operatively associated with a trained artificial classifier and wherein said set normalized signals are input through said trained artificial classifier to produce a signal indicative of cancerous and non-cancerous tissue of the subject.

6. The method for providing improved classification of breast tissue of claim 5 , wherein said computer based device is operatively associated with a plurality of trained artificial classifiers and wherein said set normalized signals are input through said trained artificial classifiers to produce signals indicative of cancerous and non-cancerous tissue of the subject.

7. The method for providing improved classification of breast tissue of claim 5 , wherein said classifier is further trained using said normalized signals.

8. The method for providing improved classification of breast tissue of claim 6 , wherein said classifiers are selected from a group of Back-Propagation, Radial Basis Function, Gaussian Mixture Model, Fuzzy Network and Support Vector Machine.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2017
From: LIFELINE BIOTECHNOLOGIES, INC.
To: CYRCADIA, INC.
Reel/Frame 042680/0456 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 24, 2009
From: ACHARYA U, RAJENDRA; KWEE, NG YIN
To: LIFELINE BIOTECHNOLOGIES, INC.
Reel/Frame 022870/0231 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 27, 2008
From: KEITH, LOUIS G.; HOLMES, JIMMY D.; REEVES, WILLIAM H.
To: LIFELINE BIOTECHNOLOGIES, INC.
Reel/Frame 021447/0061 →
Continuity (1)
Related Publication 20100056944A1 · Mar 4, 2010