Hydroamination of alkenes
View Patent ↗A method includes reacting an amino group, a composition including rhodium and an organic ligand, and a substrate having structural formula (I) in a reaction mixture. R 1 is an organic group including a sp 3 carbon atom bonded to C A . R 2 is selected from the group consisting of hydrogen, methyl, and an organic group including a sp 3 carbon atom bonded to C A . R 3 and R 4 independently are selected from the group consisting of hydrogen, methyl, and an organic group including a sp 3 carbon atom bonded to C B . The method further includes forming a hydroaminated product in the reaction mixture.
1. A composition, comprising:
a rhodium complex comprising
a central rhodium atom,
at least one ancillary ligand selected from the group consisting of cyclooctadiene, cyclooctene, acetonitrile and acetone, and
a counterion selected from the group consisting of Cl − , Br − , AcO − , TfO − , CF 3 CO 2 − , BF 4 − , ClO 4 − , ReO 4 − , AsF 6 − and SbF 6 − , and
an organic ligand, selected from the group consisting of 4,5-(bis[bis-diethylamido]-phosphonito-9,9-dimethylxanthene and 2-dicyclohexyl-phosphino-2′-(N,N-dimethylamino)-biphenyl.
2. The composition of claim 1 , where the mole ratio of ligand to rhodium is from 0.8 to 2.
3. The composition of claim 1 , where the mole ratio of ligand to rhodium is from 0.9 to 1.5.
4. The composition of claim 1 , where the mole ratio of ligand to rhodium is from 1 to 1.2.
5. A catalyst, comprising:
a rhodium complex selected from the group consisting of [Rh(COD) 2 ]BR 4 , [Rh(MeCN) 2 (COD)]BF 4 , [Rh(COE) 2 Cl] 2 and [Rh(COD)Cl] 2 and
an organic ligand, selected from the group consisting of 4,5-(bis[bis-diethylamido]-phosphonito-9,9-dimethylxanthene and 2-dicyclohexyl-phosphino-2′-(N,N-dimethylamino)-biphenyl.