IP Library Granted Patent US 8,357,102
Granted Patent B2
US 8,357,102 · App. 12/746,171 · Granted Jan 22, 2013

Devices and methods for suppression of tinnitus

Inventors: Fan-Gang Zeng (Irvine, CA); Qing Tang (Irvine, CA); Jeffrey Alan Carroll (Corona, CA)
Assignee: The Regents of the University of California
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Quick Facts
Patent No.
US 8,357,102
App. No.
12/746,171
Granted
Jan 22, 2013
Kind
B2
Abstract

Methods and devices for treating tinnitus in human or animal subjects wherein the subject is caused to perceive a tinnitus suppressing sound which fully or partially suppresses the subject's tinnitus. In some embodiments of this method, the subject selects a sound that he or she perceives to be the same as the tinnitus and that sound (or a similar sound that is complementary to the subject's perceived tinnitus) is then used as the tinnitus suppressing sound. In other embodiments, the tinnitus suppressing may be a sound that has previously been determined to suppress tinnitus in a substantial number of subjects.

Claims (42)

1. A method for treating tinnitus in a human subject, comprising:

presenting a sound to an ear of the subject;

adjusting a frequency and an intensity of the presented sound as a function of feedback from the subject to generate an adjusted sound comprising at least a perceived loudness and a matched pitch;

generating a sound comprising the matched pitch and an intensity lower than the perceived loudness;

modulating the generated sound with a sinusoid to generate a modulated sound; and

applying the modulated sound to the subject, thereby suppressing the tinnitus of the subject.

2. The method of claim 1 , wherein the modulated sound has a center frequency from about 100 Hz to about 10 kHz.

3. The method of claim 2 , wherein the modulated sound has a modulation frequency from about 0.5 Hz to about 25% of the center frequency.

4. The method of claim 1 , further comprising receiving additional feedback from the subject after applying the modulated sound and, as a function of the additional feedback, adjusting an intensity of the modulated sound within a range from zero to less than the perceived loudness.

5. The method of claim 4 , wherein the modulated sound has a center frequency from about 100 Hz and about 10 kHz.

6. The method of claim 5 , wherein the modulated sound has a modulation frequency from about 0.5 Hz to about 25% of the center frequency.

7. The method of claim 1 , wherein the generated sound is a pure tone, a click train, speech, music, band pass noise, or a white noise.

8. The method of claim 1 , said modulating comprising either amplitude modulating or frequency modulating the generated sound to generate the modulated sound.

9. The method of claim 1 , further comprising adding an offset ramp to the modulated sound.

10. The method of claim 9 , wherein duration of the offset ramp is approximately one minute or longer.

11. The method of claim 1 , wherein duration of the modulated sound is up to 8 hours.

12. The method of claim 1 , wherein said adjusting is carried out based on a double-staircase adaptive procedure.

13. The method of claim 1 , further comprising storing the modulated sound to a portable audio device.

14. A device for treating tinnitus in a human subject, said device comprising:

an audio interface for presenting sound;

an input interface for received feedback from the subject; and

a processor configured to:

presenting a sound to an ear of the subject via the audio interface;

adjusting a frequency and intensity of the presented sound as a function of feedback receiving from the subject via the input interface to generate an adjusted sound comprising at least a perceived loudness and a matched pitch;

generating a sound comprising the matched pitch and an intensity lower than the perceived loudness;

modulating the generated sound with a sinusoid to generate a modulated sound; and

applying the modulated sound to the subject via the audio interface, thereby suppressing the tinnitus of the subject.

15. The device of claim 14 , wherein the modulated sound has a center frequency from about 100 Hz to about 10 kHz.

16. The device of claim 15 , wherein the modulated sound has a modulation frequency from about 0.5 Hz to about 25% of the center frequency.

17. The device of claim 14 , wherein the processor is further configured to receive additional feedback from the subject after applying the modulated sound and, as a function of the additional feedback, adjust an intensity of the modulated sound within a range from zero to less than the perceived loudness.

18. The device of claim 17 , wherein the modulated sound has a center frequency from about 100 Hz and about 10 kHz.

19. The device of claim 18 , wherein the modulated sound has a modulation frequency from about 0.5 Hz to about 25% of the center frequency.

20. The device of claim 14 , wherein the generated sound is a pure tone, a click train, speech, music, band pass noise, or a white noise.

21. The device of claim 14 , wherein said modulating comprises either amplitude modulating or frequency modulating the generated sound to generate the modulated sound.

22. The device of claim 14 , wherein the processor is further configured to add an offset ramp to the modulated sound.

23. The device of claim 22 , wherein duration of the offset ramp is approximately one minute or longer.

24. The device of claim 14 , wherein duration of the modulated sound is up to 8 hours.

25. The device of claim 14 , wherein said adjusting is carried out based on a double-staircase adaptive procedure.

26. The device of claim 14 , wherein the processor is further configured to transfer the modulated sound to a portable audio device.

27. The device of claim 14 , wherein the audio interface is a speaker, headphones, a headset, or earbuds.

28. The device of claim 14 , wherein the input interface is configured to receive a selection from a 1-10 ranking scale for the perceived loudness of the presented sound.

29. The device of claim 14 , wherein the processor is further configured to present the sound to the ear of the subject via the audio interface for approximately 3 to 6 minutes.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2011
From: ZENG, FAN-GANG; TANG, QING; CARROLL, JEFFREY ALAN
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 025672/0349 →
CONFIRMATORY LICENSE Recorded Jun 10, 2010
From: UNIVERSITY OF CALIFORNIA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024513/0826 →
Continuity (2)
Provisional Application 60992638 · Dec 5, 2007
Related Publication 20110105967A1 · May 5, 2011