IP Library › Granted Patent US 8,389,677
Granted Patent B2
US 8,389,677 · App. 13/008,211 · Granted Mar 5, 2013

Antioxidant polypeptide and a process for isolation and purification of the same

Inventor: Leela Srinivas (Mandya District, IN)
Assignee: Adichunchanagiri Biotechnology and Cancer Research Institute
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Quick Facts
Patent No.
US 8,389,677
App. No.
13/008,211
Granted
Mar 5, 2013
Kind
B2
Abstract

A polypeptide is isolated from Turmeric ( Curcuma longa Linn) having molecular weight of about 8,000 Daltons. The polypeptide is highly water-soluble and absolutely non-toxic antioxidant, which is isolated using boiling water extraction. The polypeptide is an excellent antioxidant working at low concentration (of about 80 nM) to quench lipid peroxidation up to 90%. The polypeptide is highly effective against oxidative stress related diseases like arthritis, atherosclerosis, cardiovascular diseases, neurodegenerative diseases, cancer, cataract, malaria, bacterial and fungal infectious diseases.

Claims (1)

1. A purified antioxidant polypeptide of SEQ ID NO: 1 obtained from Turmeric ( Curcuma longa ), and having molecular weight of about 8 kDa as determined by gel-permeation.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 18, 2011
From: SRINIVAS, LEELA
To: ADICHUNCHANAGIRI BIOTECHNOLOGY AND CANCER RESEARCH INSTITUTE
Reel/Frame 025652/0694 →
Priority Claims (1)
IN 145/CHE/2010 · Jan 22, 2010 · national
Continuity (1)
Related Publication 20110184146A1 · Jul 28, 2011