IP Library › Granted Patent US 8,389,682
Granted Patent B2
US 8,389,682 · App. 12/523,425 · Granted Mar 5, 2013

Inhibiting

Inventors: Carlos Arrecubieta (New York, NY); Mei-Ho Lee (New York, NY); Franklin D. Lowy (Hastings-on-Hudson, NY)
Assignee: Trustees of Columbia University in the City of New York
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Quick Facts
Patent No.
US 8,389,682
App. No.
12/523,425
Granted
Mar 5, 2013
Kind
B2
Abstract

The invention relates to Staphylococcus epidermidis peptides, antibodies and nucleic acids that can inhibit Staphylococcus epidermidis infection of a mammalian subject and colonization of a medical device in the mammal.

Claims (5)

1. An isolated Staphylococcus epidermidis SdrF peptide consisting of any of SEQ ID NOs: 3-9, or 31.

2. A composition comprising a pharmaceutically acceptable carrier and the peptide of claim 1 .

3. A method of treating or inhibiting Staphylococcus epidermidis infection in a mammal comprising administering to the mammal a composition comprising an isolated Staphylococcus epidermidis SdrF peptide consisting of any of SEQ ID NO:3-9, 31, or a combination thereof to thereby treat or inhibit Staphylococcus epidermidis infection in a mammal.

4. The method of claim 3 , wherein the method inhibits Staphylococcus epidermidis colonization of a medical device in the mammal.

5. A composition comprising an isolated Staphylococcus epidermidis SdrF peptide consisting of any of SEQ ID NOS:3-9, 31, or a combination thereof.

Assignments (3)
CONFIRMATORY LICENSE Recorded May 18, 2017
From: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 042420/0372 →
CONFIRMATORY LICENSE Recorded Aug 23, 2010
From: COLUMBIA UNIV NEW YORK MORNINGSIDE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024869/0239 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 7, 2009
From: ARRECUBIETA, CARLOS; LEE, MEI-HO; LOWY, FRANKLIN D.
To: TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE
Reel/Frame 023622/0027 →
Continuity (2)
Provisional Application 60885098 · Jan 16, 2007
Related Publication 20110117099A1 · May 19, 2011