Method for the treatment of biological tissue of animal or human origin, such as porcine, bovine pericardium or human cadaver heart valves, and biological tissue treated accordingly

1. A method for the treatment of biological tissue of animal or human origin so as to increase the biocompatibility, the method comprising:

treating the tissue with an ionized plasma gas and coating the plasma treated tissue with a biocompatible, metal-containing coating selected from the group consisting of Ti, Ta, Nb, Zr, Hf, Ir, Au, Pd, Pt, Ag and Cu, said tissue being dried before the treatment by means of the plasma gas method, wherein the drying takes place by means of the influence of a vacuum and temperature.

2. The method according to claim 1 , wherein nitrogen, hydrogen, argon or preferably oxygen is used as the ionized gas in a plasma gas method as the plasma treatment.

3. The method according to claim 2 , wherein the energy input for the production of the plasma takes place by means of a high-frequency electromagnetic field, in particular a microwave field.

4. The method according to claim 1 , wherein the plasma treatment takes place with an atmospheric plasma using a plasma jet under atmospheric conditions.

5. The method according to claim 1 , wherein moisture is supplied to the dried tissue after the plasma treatment.

6. The method according to claim 1 , wherein the metal-containing coating is applied by means of a Plasma Assisted Chemical Vapor Deposition (PACVD) method.

7. The method according to claim 1 , wherein the tissue is selected from the group consisting of porcine heart valves, valves of bovine pericardium, or human cadaver heart valves.

8. The method according to claim 1 , wherein said tissue is treated with glutaraldehyde prior to treating the tissue with said ionized plasma gas.

9. A method, comprising:

providing an ionized plasma gas;

providing a biological tissue;

applying said ionized plasma gas to said biological tissue to form an ionized plasma treating tissue, the biological tissue being dried before applying the ionized plasma gas, wherein the drying takes place via a vacuum and temperature;

applying a coating to said ionized plasma treating tissue, said coating comprising a biocompatible metal, said biocompatible metal being selected from the group consisting of Ti, Ta, Nb, Zr, Hf, Ir, Au, Pd, Pt, Ag and Cu.

10. The method according to claim 9 , wherein the biological tissue is selected from the group consisting of porcine heart valves, valves of bovine pericardium, or human cadaver heart valves.

11. The method according to claim 9 , wherein said tissue is treated with glutaraldehyde prior to treating the tissue with said ionized plasma gas.

12. The method according to claim 11 , wherein the energy input for the production of the plasma takes place by means of a high-frequency electromagnetic field, in particular a microwave field.

13. The method according to claim 9 , wherein the plasma treatment takes place with an atmospheric plasma using a plasma jet under atmospheric conditions.

14. The method according to claim 9 , wherein moisture is supplied to the dried tissue after applying the ionized plasma gas.