Granted Patent
B2
US 8,431,393 · App. 13/011,174 · Granted Apr 30, 2013
AIMP2-DX2 gene and its uses
Assignee:
Neomics Co., Ltd.
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Abstract
The present invention relates to a variant of AIMP2 lacking exon 2 gene, named as AIMP2-DX2 gene, which is specifically expressed in cancer cells. The AIMP2-DX2 gene and siRNA targeting AIMP2-DX2 can be successfully used in the development of diagnosis and treatment of cancer.
Claims (4)
1. An isolated nucleic acid molecule encoding the AIMP2-DX2 protein having the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 17.
2. The isolated nucleic acid molecule according to claim 1 , wherein the nucleic acid molecule comprises a nucleotide sequence of SEQ ID NO:1 or SEQ ID NO: 16.
3. An expression vector which comprises the nucleic acid molecule of claim 1 .
4. An isolated cell comprising the expression vector of claim 3 .
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded May 15, 2015
From: NEOMICS CO., LTD.
To: MEDICINAL BIOCONVERGENCE RESEARCH CENTER
Reel/Frame 035651/0204 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 1, 2012
From: KIM, SUNGHOON; CHOI, JIN WOO
To: SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION
Reel/Frame 028700/0174 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 1, 2012
From: SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION
To: NEOMICS CO., LTD.
Reel/Frame 028700/0227 →
Priority Claims (2)
KR 10-2004-0097164
· Nov 24, 2004
· national
KR 10-2005-0039073
· May 10, 2005
· national
Continuity (3)