Fluid processing and control
A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers.
1. A fluid control and processing system comprising:
a housing having a plurality of chambers and at least one separation channel; and
a valve body including a fluid processing region continuously coupled fluidicly with a fluid displacement region, the fluid displacement region including or being connected to a means that depressurizes the fluid displacement region to draw fluid into the fluid displacement region and pressurizes the fluid displacement region to expel fluid from the fluid displacement region, the valve body including at least one external port, the fluid processing region being fluidicly coupled with the at least one external port, the fluid displacement region being fluidicly coupled with at least one external port of the valve body, and the valve body being adjustable with respect to the housing to allow the at least one external port to be placed selectively in fluidic communication with the plurality of chambers and with the at least one separation channel.
2. The system of claim 1 , further comprising a plurality of electrodes coupled to the housing to apply an electric field across at least a portion of the separation channel.
3. The system of claim 2 , wherein the electrodes comprise a pair of metal tubes at the two opposite ends of the separation channel.
4. The system of claim 1 , further comprising reservoirs fluidicly coupled to opposite ends of the separation channel, and a reservoir port fluidicly coupled to one of the reservoirs for communicating with the at least one external port of the valve body.
5. The system of claim 1 , wherein at least one of the chambers is a reagent chamber containing dried or lyophilized reagents.
6. A method for controlling fluid flow between the valve body, the plurality of chambers, and the at least one separation channel of the system of claim 1 , the method comprising:
adjusting the valve body with respect to the plurality of chambers and the at least one separation channel to place the at least one external port selectively in fluidic communication with the plurality of chambers and the separation channel.
7. The method of claim 6 , further comprising applying an electric field across at least a portion of the separation channel.
8. The method of claim 6 , wherein the external port is placed in fluidic communication with the separation channel via a reservoir fluidicly coupled to one end of the separation channel, the reservoir having a reservoir port for communicating with the at least one external port of the valve body.
9. The method of claim 6 , further comprising optically detecting species bands in the separation channel.