IP Library › Granted Patent US 8,436,183
Granted Patent B2
US 8,436,183 · App. 13/361,082 · Granted May 7, 2013

Synthetic multimerizing agents

Inventors: Dennis A. Holt (Royersford, PA); Terence P. Keenan (Bay Shore, NY); Tao Guo (Dayton, NJ); Edgardo Laborde (Foster City, CA); Wu Yang (Princeton, NJ)
Assignee: ARIAD Pharmaceuticals, Inc.
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Quick Facts
Patent No.
US 8,436,183
App. No.
13/361,082
Granted
May 7, 2013
Kind
B2
Abstract

New compounds are disclosed for multimerizing immunophilins and proteins containing immunophilin or immunophilin-related domains. The compounds are of the formula M-L-Q where M is a synthetic ligand for an FKBP protein.

Claims (4)

1. A compound of the formula

or a salt thereof.

2. A compound of the formula

or a salt thereof.

Continuity (11)
Continuation 10461705 · Jun 13, 2003
Continuation 10086770 · Feb 28, 2002
Continuation 09690581 · Oct 17, 2000
Continuation 08808274 · Feb 28, 1997
Continuation In Part 08793016 · Dec 1, 1997
Continuation In Part 08479694 · Jun 7, 1995
Continuation In Part 08292598 · Aug 18, 1994
Provisional Application 60033035 · Dec 10, 1996
Provisional Application 60024861 · Aug 28, 1996
Provisional Application 60012432 · Feb 28, 1996
Related Publication 20120130076A1 · May 24, 2012