IP Library Granted Patent US 8,444,958
Granted Patent B2
US 8,444,958 · App. 10/469,478 · Granted May 21, 2013

Compositions having anti-dental caries function

Inventors: Hiroshi Kamasaka (Osaka, JP); Takahisa Nishimura (Nara, JP); Kenji Too (Osaka, JP); Takashi Kuriki (Osaka, JP); Shigetaka Okada (Nara, JP); Reiichiro Sakamoto (Ibaraki, JP); Toshiyuki Kimura (Chiba, JP); Nobuo Uotsu (Chiba, JP)
Assignee: Ezaki Glico Co., Ltd.
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Quick Facts
Patent No.
US 8,444,958
App. No.
10/469,478
Granted
May 21, 2013
Kind
B2
Abstract

The present invention relates to dietary compositions and oral compositions having an anti-dental caries function. The present invention provides dietary compositions and oral compositions having an anti-dental caries function which contain a buffering agent having a pH buffering action in the oral cavity.

Claims (24)

1. A dietary composition which requires mastication having an anti-dental caries function, wherein the composition comprises:

(i) a buffering agent having a pH buffering action in the oral cavity at a concentration in the range from 0.01% by weight to 20% by weight, and

(ii) a calcium preparation,

wherein the buffering agent is a phosphorylated oligosaccharide in the form of a sodium salt or a calcium salt,

wherein the concentrations of the buffering agent and the calcium preparation in the composition are selected to provide a Ca/P ratio in the saliva after mastication that is substantially 1.0 to 1.67;

wherein the phosphorylated oligosaccharide of the phosphorylated oligosaccharide in the form of a sodium salt or a calcium salt is a glucan consisting of 3 to 5 glucoses with α-1,4 linkages, one phosphate group being linked to the glucan, or glucan consisting of 2 to 8 glucoses with α-1,4 linkages, two phosphate groups being linked to the glucan; and

wherein the calcium preparation is selected from the group consisting of calcium carbonate, calcium chloride, calcium lactate, calcium gluconate, whey calcium, organic acid calcium, colloidal calcium carbonate, casein phosphopeptide calcium, and calcium fluoride.

2. An oral composition having an anti-dental caries function, wherein the composition comprises:

(i) a buffering agent having a pH buffering action in the oral cavity at a concentration in the range from 0.01% by weight to 20% by weight, and

(ii) a calcium preparation,

wherein the buffering agent is a phosphorylated oligosaccharide in the form of a sodium salt or a calcium salt,

wherein the concentrations of the buffering agent and the calcium preparation in the composition are selected to provide a Ca/P ratio in the saliva of substantially 1.0 to 1.67;

wherein the phosphorylated oligosaccharide of the phosphorylated oligosaccharide in the form of a sodium salt or a calcium salt is a glucan consisting of 3 to 5 glucoses with α-1,4 linkages, one phosphate group being linked to the glucan, or glucan consisting of 2 to 8 glucoses with α-1,4 linkages, two phosphate groups being linked to the glucan; and

wherein the calcium preparation is selected from the group consisting of calcium carbonate, calcium chloride, calcium lactate, calcium gluconate, whey calcium, organic acid calcium, colloidal calcium carbonate, casein phosphopeptide calcium, and calcium fluoride,

wherein the oral composition is in the form of a troche or lozenge.

3. A dietary composition having an anti-dental caries function, wherein the composition comprises:

(i) a buffering agent having a pH buffering action in the oral cavity at a concentration in the range from 0.01% by weight to 20% by weight, and

(ii) a calcium preparation,

wherein the buffering agent is a phosphorylated oligosaccharide in the form of a sodium salt or a calcium salt;

wherein the concentrations of the buffering agent and the calcium preparation in the composition are selected to provide a Ca/P ratio in the saliva of substantially 1.0 to 1.67;

wherein the phosphorylated oligosaccharide of the phosphorylated oligosaccharide in the form of a sodium salt or a calcium salt is a glucan consisting of 3 to 5 glucoses with α-1,4 linkages, one phosphate group being linked to the glucan, or glucan consisting of 2 to 8 glucoses with α-1,4 linkages, two phosphate groups being linked to the glucan; and

wherein the calcium preparation is selected from the group consisting of calcium carbonate, calcium chloride, calcium lactate, calcium gluconate, whey calcium, organic acid calcium, colloidal calcium carbonate, casein phosphopeptide calcium, and calcium fluoride, wherein the dietary composition is in the form of candy, soft candy or chewing gum.

4. A dietary composition according to claim 1 , wherein the dietary composition is in the form of chewing gum.

5. A dietary composition according to claim 1 , wherein the buffering agent is a phosphorylated oligosaccharide in the form of a calcium salt.

Assignments (2)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF ASSIGNEE AND SPELLING OF FIRST NAMES FOR TWO INVENTORS PREVIOUSLY RECORDED ON REEL 014180 FRAME 0123. ASSIGNOR(S) HEREBY CONFIRMS THE THE NAME OF THE ASSIGNEE IS EZAKI GLICO CO., LTD. THE CORRECT SPELLING SHOULD BE SHIGETAKA OKADA AND REIICHIRO SAKAMOTO.. Recorded Apr 9, 2013
From: KAMASAKA, HIROSHI; NISHIMURA, TAKAHISA; TOO, KENJI; KURIKI, TAKASHI; OKADA, SHIGETAKA; SAKAMOTO, REIICHIRO; KIMURA, TOSHIYUKI; UOTSU, NOBUO
To: EZAKI GLICO CO., LTD.
Reel/Frame 030177/0204 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2003
From: KAMASAKA, HIROSHI; NISHIMURA, TAKAHISA; TOO, KENJI; KURIKI, TAKASHI; OKADA, SHIGETAKI; SAKAMOTO, RIICHIRO; KIMURA, TOSHIYUKI; UOTSU, NOBUO
To: EZAKI GILCO CO., LTD.
Reel/Frame 014180/0123 →
Priority Claims (2)
JP 2001-56010 · Feb 28, 2001 · national
JP 2001-56011 · Feb 28, 2001 · national
Continuity (1)
Related Publication 20040105823A1 · Jun 3, 2004