High temperature thermal therapy of breast cancer
A method is described for preventing breast cancer recurrence after surgical removal of a breast cancer mass. Specifically, the method is thermal treatment of breast tissue surrounding a cavity after lumpectomy for breast cancer. Delivery of a heated fluid is through a balloon catheter to the cavity generated after lumpectomy with the goal of ablating the surrounding tissue, including transformed cells that were not removed through surgery. A balloon and controller were designed for this application.
1. A method to kill cells surrounding a cavity with heated fluid using a balloon catheter wherein the cavity is caused by the removal of an undesirable growth and wherein the cavity may have various shapes, the method comprising:
(a) conforming the balloon to the shape of the cavity by determining the volume of the cavity and providing sufficient fluid to fill the cavity based on the volume;
(b) reaching a temperature in the range of 80°-97° C. in the fluid to achieve a temperature in tissues surrounding the cavity that kills cells; and
(c) spacing a plurality of temperature sensors from the cavity, wherein a number and placement of the temperature sensors are selected based on a shape and a size of the cavity.
2. The method of claim 1 , further including monitoring a temperature of the tissue surrounding the cavity.