Quorum sensing inhibitor
View Patent ↗The present invention provides a control agent that is extremely effective in controlling bacterial diseases. The quorum sensing inhibitor and bacterial disease control agent for agricultural and horticultural use of the present invention contain a pyrimidinone compound represented by General Formula (1): wherein R 1 represents a C 1-5 alkyl group or a phenyl group, and R 2 represents a hydrogen atom or a C 1-5 alkyl group, provided that R 1 cannot be a methyl group when R 2 represents a hydrogen atom.
1. A biofilm formation inhibitor and/or biofilm remover of Burkholderia aeruginosa and/or periodontopathic bacteria comprising:
a pyrimidinone compound represented by General Formula (1):
wherein R 1 is a C 1-5 alkyl group or a phenyl group; and R 2 is a hydrogen atom or a C 1-5 alkyl group; provided that when R 2 is a hydrogen atom, R 1 cannot be a methyl group; and
an additive selected from the group consisting of antibiotics, antimicrobial agents, bactericides, antiseptic agents, builders, bleaching agents, and enzymes.
2. The biofilm formation inhibitor and/or biofilm remover of Burkholderia aeruginosa and/or periodontopathic bacteria according to claim 1 , wherein R 1 is a C 2-5 alkyl group, and R 2 is a hydrogen atom.
3. The biofilm formation inhibitor and/or biofilm remover of Burkholderia aeruginosa and/or periodontopathic bacteria according to claim 1 , wherein R 1 is a C 1-3 alkyl group, and R 2 is a C 1-5 alkyl group.
4. A bacterial disease control agent for agricultural and horticultural use comprising:
a pyrimidinone compound represented by General Formula (1):
wherein R 1 is a C 1-5 alkyl group or a phenyl group; and R 2 is a hydrogen atom or a C 1-5 alkyl group; provided that when R 2 is a hydrogen atom, R 1 cannot be a methyl group; and
an additive selected from the group consisting of herbicides, insecticides, nematicides, miticides, bactericides, plant growth regulators, synergists, and soil conditioners.
5. The bacterial disease control agent for agricultural and horticultural use according to claim 4 , wherein R 1 is a C 2-5 alkyl group, and R 2 is a hydrogen atom.
6. The bacterial disease control agent for agricultural and horticultural use according to claim 4 , wherein R 1 is a C 1-3 alkyl group, and R 2 is a C 1-5 alkyl group.
7. The bacterial disease control agent for agricultural and horticultural use according to claim 6 ,
wherein R 2 is a methyl group.
8. An agricultural and horticultural bacterial disease-control method, comprising the step of:
applying to cultivated plants a pyrimidinone compound represented by General Formula (1):
wherein R 1 is a C 1-5 alkyl group or a phenyl group; and R 2 is a hydrogen atom or a C 1-5 alkyl group; provided that when R 2 is a hydrogen atom, R 1 cannot be a methyl group.
9. A method of preventing the formation of a biofilm formed by Burkholderia aeruginosa and/or periodontopathic bacteria or a method of removing a biofilm formed by Burkholderia aeruginosa and/or periodontopathic bacterial wherein the method comprises employing a pyrimidinone compound represented by General Formula (1):
wherein R 1 is a C 1-5 alkyl group or a phenyl group; and R 2 is a hydrogen atom or a C 1-5 alkyl group; provided that when R 2 is a hydrogen atom, R 1 cannot be a methyl group.