Synthetic lipid A derivative
View Patent ↗The invention provides functionalized monosaccharides and disaccharides suitable for use in synthesizing a lipid A derivative, as well as methods for synthesizing and using a synthetic lipid A derivative.
1. An isolated, synthetic lipid A derivative selected from the group consisting of compounds:
2. A pharmaceutical composition comprising:
an effective amount of a lipid A derivative of claim 1 ; and
a pharmaceutically acceptable carrier.
3. The pharmaceutical composition of claim 2 comprising:
a first component comprising an effective amount of an active agent;
a second component comprising a lipid A derivative of claim 1 , wherein the lipid A derivative functions as an adjuvant; and
a pharmaceutically acceptable carrier.
4. The pharmaceutical composition of claim 3 wherein the active agent comprises an antigen or immunogen.