IP Library Granted Patent US 8,586,631
Granted Patent B2
US 8,586,631 · App. 13/764,126 · Granted Nov 19, 2013

Calcilytic compounds

Inventors: Robert W. Marquis (Collegeville, PA); Linda N. Casillas (Collegeville, PA); Joshi M. Ramanjulu (Collegeville, PA); James Francis Callahan (King of Prussia, PA)
Assignee: GlaxoSmithKline, LLC
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Quick Facts
Patent No.
US 8,586,631
App. No.
13/764,126
Granted
Nov 19, 2013
Kind
B2
Abstract

Novel calcilytic compounds and methods of using them are provided.

Claims (6)

1. The compound 3-{3,4-Difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-dimethyl-ethylamino)-propoxy]-phenyl}-propionic acid ethyl ester hydrochloride.

2. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable diluent or excipient.

3. The compound 3-{3,4-Difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-dimethyl-ethylamino)-propoxy]-phenyl}-propionic acid ethyl ester.

4. A pharmaceutical composition comprising the compound of claim 3 and a pharmaceutically acceptable diluent or excipient.

5. A pharmaceutically acceptable salt of the compound 3-{3,4-Difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-dimethyl-ethylamino)-propoxy]-phenyl}-propionic acid ethyl ester.

6. A pharmaceutical composition comprising the compound of claim 5 and a pharmaceutically acceptable diluent or excipient.

Assignments (2)
CHANGE OF NAME Recorded Mar 6, 2013
From: SMITHKLINE BEECHAM CORPORATION
To: GLAXOSMITHKLINE LLC
Reel/Frame 029939/0338 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2013
From: MARQUIS, ROBERT W.; CASILLAS, LINDA N.; RAMANJULU, JOSHI M.; CALLAHAN, JAMES FRANCIS
To: SMITHKLINE BEECHAM CORPORATION
Reel/Frame 029921/0670 →
Continuity (5)
Continuation 12894644 · Sep 30, 2010
Continuation 12393284 · Feb 26, 2009
Division 10536416
Provisional Application 60429105 · Nov 26, 2002
Related Publication 20130158114A1 · Jun 20, 2013