Biliquid foams stable dispersions thereof and a corresponding process of manufacturing
A biliquid foam includes from 10% to 98% by weight of a non-polar liquid other than a fuel and from 2 to 88% by weight of a continuous phase polar liquid comprising a C 1 -C 4 alcohol, a liquid polyethylene glycol, ethylene glycol or propylene glycol, or mixtures thereof, in an amount of at least 65% by weight, relative to the weight of the continuous phase, wherein the biliquid foam is stabilized with an amount of from 0.05% to 2% by weight based on the total formulation of a surfactant which is selected from castor oil/poly(alkylene glycol) adducts containing from 20 to 50 alkoxy groups, a C 8 -C 24 fatty acid or hydrogenated castor oil/poly(alkylene glycol) adducts containing from 20 to 60 alkoxy groups, or mixtures thereof.
1. A biliquid foam comprising;
from 10% to 98% by weight of a non polar liquid comprising a mineral oil, a siloxane, an emollient ester, a glyceride, a lanolin oil, a natural oil, oleyl alcohol, isoeicosane or isooctahexacontane, or mixtures thereof; and
from 2 to 88% by weight of a continuous phase polar liquid comprising a C 1 -C 4 alcohol, a liquid polyethylene glycol, ethylene glycol or propylene glycol, or mixtures thereof, in an amount of at least 65% by weight, relative to the weight of the continuous phase,
wherein the biliquid foam is stabilized with an amount of from 0.05% to 2% by weight based on the total formulation of a surfactant which is selected from the group consisting of castor oil/poly(alkylene glycol) adducts containing from 20 to 50 alkoxy groups, a C 8 -C 24 fatty acid or hydrogenated castor oil/poly(alkylene glycol) adducts containing from 20 to 60 alkoxy groups, or mixtures thereof.
2. The biliquid foam as claimed in claim 1 , wherein the amount of surfactant is about 1% by weight based on the total formulation.
3. The biliquid foam as claimed in claim 2 , wherein the surfactant comprises a hydrogenated castor oil/polyethylene glycol adduct containing from 40 to 60 ethoxy groups.
4. The biliquid foam as claimed in claim 2 , wherein the surfactant comprises a castor oil/poly(alkylene glycol) adduct containing 25 to 45 ethoxy groups.
5. The biliquid foam as claimed in claim 1 , wherein the siloxane comprises dimethicone, cyclomethicone, dimethiconol, dimethicone copolyol, octamethylcyclotetrasiloxane, octamethylcyclo-pentasiloxane, decamethylcyclopentasiloxane, or mixtures thereof.
6. The biliquid foam as claimed in claim 1 , wherein the emollient ester is isopropyl isostearate, lanolate, myristate or palmitate, or octyl palmitate, or mixtures thereof.
7. The biliquid foam as claimed in claim 1 , wherein the surfactant comprises a hydrogenated castor oil/polyethylene glycol adduct containing from 40 to 60 ethoxy groups.
8. The biliquid foam as claimed in claim 1 , wherein the surfactant comprises a castor oil/poly(alkylene glycol) adduct containing 25 to 45 ethoxy groups.
9. The biliquid foam as claimed in claim 1 , wherein the polar liquid is aqueous and comprises from 70% to 99% by weight of the C 1 -C 4 , alcohol, liquid polyethylene glycol, ethylene glycol or propylene glycol, or mixtures thereof.
10. A stable dispersion comprising from 1 to 80% by weight of a biliquid foam as claimed in claim 1 , and from 99 to 20% by weight of an aqueous gel.
11. The stable dispersion as claimed in claim 10 , wherein the aqueous gel constitutes from 50 to 99% by weight thereof.
12. The stable dispersion as claimed in claim 10 , wherein the aqueous gel comprises a colloidal polymer or gum suspended in water.
13. The stable dispersion as claimed in claim 10 which includes therein at least one pharmaceutical or cosmetic compound therein.
14. A process for preparing a stable dispersion which comprises from 1 to 80% by weight of a biliquid foam as claimed in claim 1 , and from 99 to 20% by weight of an aqueous gel, which process comprising mixing together the biliquid foam and the aqueous gel.
15. A process as claimed in claim 14 , wherein the stable dispersion also comprises a pharmaceutical compound.
16. A process as claimed in claim 15 in which the stable dispersion is in a topical form for application to the skin and contains a non steroidal anti-flammatory drug, an anti-acne compound, anti-viral or anti-bacterial compound.
17. A process as claimed in claim 15 in which the stable dispersion is in the form of a transdermal delivery device or in a cream or gel preparation and which contains nicotine, estradiol, nitroglycerin, testosterone or scopolamine as the active ingredient.
18. A process as claimed in claim 14 , wherein the stable dispersion also comprises a cosmetic compound.
19. A process as claimed in claim 18 in which the stable dispersion is an anti-cellulite cream or an aftershave lotion.
20. A process as claimed in claim 14 , wherein the stable dispersion also comprises a disinfectant compound.