Pyrazole amide compounds and uses thereof

1. A pyrazole amide compound represented by the following formula (I):

wherein:

R 1 is selected from H, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkoxycarbonyl, C 1 -C 12 haloalkoxycarbonyl, C 1 -C 12 alkylaminocarbonyl, C 1 -C 12 haloalkylaminocarbonyl, C 3 -C 6 cycloalkyl or R 8 ;

R 2 is selected from H, halogen, CN, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 cyanoalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 haloalkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylthioC 1 -C 12 alkyl, C 1 -C 12 haloalkylthioC 1 -C 12 alkyl, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 3 -C 6 cycloalkyl or R 8 ;

R 3 is selected from H or C 1 -C 12 alkyl; m is selected from 0 to 5;

R 4 is selected from halogen, CN, CONH 2 , CSNH 2 , NO 2 , C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 haloalkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylthioC 1 -C 12 alkyl, C 1 -C 12 haloalkylthioC 1 -C 12 alkyl, C 1 -C 12 alkylamino, C 1 -C 12 haloalkylamino, C 2 C 12 dialkylamino, piperidyl, pyrrolidyl, N-methyl piperazinyl, morpholinyl, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkenoxy, C 2 -C 12 haloalkenoxy, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 2 -C 12 alkynoxy, C 2 -C 12 haloalkynoxy, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl or R 8 ; n is selected from 0 to 4;

R 5 is selected from H, C 1 -C 12 alkyl, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkylamino, C 1 -C 12 haloalkylamino, C 2 -C 12 dialkylamino, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylcarbonylamino,

 or R 8 ;

R 6 is selected from H, CN, SCN, H(C═O), C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkylcarbonyl, C 1 -C 12 alkoxycarbonyl, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 hydroxyalkyl, C 3 -C 6 cycloalkyl or R 8 ; p is selected from 0 to 5;

X 1 is selected from H, halogen, NO 2 , CN, SCN, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C r C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfinyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 haloalkylthio, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 haloalkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylthioC 1 -C 12 alkyl or C 1 -C 12 haloalkylthioC 1 -C 12 alkyl;

X 2 , X 3 , X 4 and X 5 may be the same or different, mutually independently selected from H, halogen, CN, NO 2 , OH, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio or C 1 -C 12 alkylsulfonyl;

Q 1 and Q 2 may be the same or different, mutually independently selected from H, NH 2 , OH, CN, SCN, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfinyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylamino, C 2 -C 12 dialkylamino, piperidyl, pyrrolidyl, N-methyl piperazinyl, morpholinyl, H(C═O), C 1 -C 12 alkylaminocarbonyl, C 1 -C 12 alkoxycarbonyl, C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylaminothio, C 2 -C 12 dialkylaminothio, C 3 -C 6 cycloalkyl or R 8 ;

Y is selected from O, S or NR 7 ;

Z is selected from O or S;

R 7 is selected from H, CN, NH 2 , OH, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 12 alkoxy, C 1 -C 12 haloalkoxy, C 3 -C 6 cycloalkyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 cyanoalkoxy, C 1 -C 12 alkylamino, C 1 -C 12 haloalkylamino, C 2 -C 12 dialkylamino, piperidyl, Pyrrolidyl, N-methylpiperazinyl, morpholinyl, 2,6-dimethylmorpholinyl, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkenoxy, C 2 -C 12 haloalkenoxy, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 2 -C 12 alkynoxy, C 2 -C 12 haloalkynoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylcarbonylamino,

 or R 8 ;

Or, when Y is selected from NR 7 , NR 7 and R 5 form a unsubstituted or substituted five-membered or six-membered ring with 1-4 substitutents selected independently from C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy or C 3 -C 6 cycloalkyl;

R 8 is selected from phenyl, benzoyl, phenoxycarbonyl, phenylaminocarbonyl, phenylC 1 -C 6 alkyl, naphthyl, naphthylC 1 -C 6 alkyl, heteroaryl, heteroarylcarbonyl, heteroaryloxycarbonyl, heteroarylaminocarbonyl or heteroarylC 1 -C 6 alkyl, which can be unsubstituted or further substituted with 1-5 substitutents, the substitutent(s) mentioned was (were) selected independently from halogen, NO 2 , CN, SH, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 3 -C 12 cycloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 3 -C 12 alkenoxy, C 3 -C 12 haloalkenoxy, C 3 -C 12 alkynoxy, C 3 -C 12 haloalkynoxy, C 1 -C 12 alkylsulfinyl, C 1 -C 12 haloalkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkylcarbonyloxy, C 1 -C 12 alkylcarbonylamino, C 1 -C 12 alkylsulfonyloxy, C 1 -C 12 alkoxycarbonyl, C 1 -C 12 alkoxyC 1 -C 12 alkoxy, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkoxycarbonylamino, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkoxy, CHO, CO 2 H, CO 2 Na, CO 2 NH 4 , NR 9 R 10 , C(═O)NR 9 R 10 , OC(═O)NR 9 R 10 , C(═S)NR 9 R 10 or SO 2 NR 9 R 10 ;

R 9 and R 10 may be the same or different, mutually independently selected from H, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 3 -C 6 cycloalkyl or R 8 ;

(CHR 3 )mCON(Q 2 ) links with phenyl ring at the 2, 3 or 4-position.

2. The compound according to claim 1 , wherein:

R 1 is selected from H, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 cyanoalkyl, C 1 -C 6 alkoxyC 1 -C 6 alkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, C 1 -C 6 alkylaminocarbonyl, C 1 -C 6 haloalkylaminocarbonyl, C 3 -C 6 cycloalkyl or R 8 ;

R 2 is selected from H, halogen, CN, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 cyanoalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkoxyC 1 -C 6 alkyl, C 1 -C 6 haloalkoxyC 1 -C 6 alkyl, C 1 -C 6 alkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 3 -C 6 cycloalkyl or R 8 ;

R 3 is selected from H or C 1 -C 4 alkyl; m is selected from 1 to 3;

R 4 is selected from halogen, CN, CONH 2 , CSNH 2 , NO 2 , C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 alkylthio, C 1 -C 4 haloalkylthio, C 1 -C 4 alkoxyC 1 -C 4 alkyl, C 1 -C 4 haloalkoxyC 1 -C 4 alkyl, C 1 -C 4 alkylthioC 1 -C 4 alkyl, C 1 -C 4 haloalkylthioC 1 -C 4 alkyl, C 1 -C 4 alkylamino, C 1 -C 4 haloalkylamino, C 2 -C 4 dialkylamino, piperidyl, Pyrrolidyl, N-methyl piperazinyl, morpholinyl, C 2 -C 4 alkenyl, C 2 -C 4 haloalkenyl, C 2 -C 4 alkenoxy, C 2 -C 4 haloalkenoxy, C 2 -C 4 alkynyl, C 2 -C 4 haloalkynyl, C 2 -C 4 alkynoxy, C 2 -C 4 haloalkynoxy, C 1 -C 4 alkylsulfinyl, C 1 -C 4 alkylsulfonyl or R 8 ; n is selected from 0 to 3;

R 5 is selected from H, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxyC 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 4 cyanoalkyl, C 1 -C 4 alkylamino, C 1 -C 4 haloalkylamino, C 2 -C 6 dialkylamino, C 2 -C 4 alkenyl, C 2 -C 4 haloalkenyl, C 2 -C 4 alkynyl, C 2 -C 4 haloalkynyl, C 1 -C 4 alkylsulfonyl, C 1 -C 4 haloalkylsulfonyl, C 1 -C 4 alkylcarbonyl, C 1 -C 4 haloalkylcarbonyl, C 1 -C 4 alkyloxycarbonylC 1 -C 4 alkyl, C 1 -C 4 alkylcarbonylamino,

 or R 8 ;

R 6 is selected from H, CN, SCN, H(C═O), C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 alkylthio, C 1 -C 4 haloalkylthio, C 1 -C 4 alkylcarbonyl, C 1 -C 4 alkyloxycarbonyl, C 1 -C 4 alkylsulfinyl, C 1 -C 4 alkylsulfonyl, C 1 -C 4 cyanoalkyl, C 1 -C 4 hydroxyalkyl, C 3 -C 6 cycloalkyl or R 8 ; p is selected from 0 to 4;

X 1 is selected from H, halogen, NO 2 , CN, SCN, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 alkylthio, C 1 -C 4 alkylsulfinyl, C 1 -C 4 alkylsulfonyl, C 1 -C 4 haloalkylsulfinyl, C 1 -C 4 haloalkylsulfonyl, C 1 -C 4 haloalkylthio, C 1 -C 4 alkoxyC 1 -C 4 alkyl, C 1 -C 4 haloalkoxyC 1 -C 4 alkyl, C 1 -C 4 alkylthioC 1 -C 4 alkyl or C 1 -C 4 haloalkylthioC 1 -C 4 alkyl;

X 2 , X 3 , X 4 and X 5 may be the same or different, mutually independently selected from H, halogen, CN, NO 2 , OH, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 alkylthio or C 1 -C 4 alkylsulfonyl;

Q 1 and Q 2 may be the same or different, mutually independently selected from H, NH 2 , OH, CN, SCN, C 1 -C 4 cyanoalkyl, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkylcarbonyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 alkoxyC 1 -C 4 alkyl, C 1 -C 4 alkylsulfinyl, C 1 -C 4 alkylsulfonyl, C 1 -C 4 haloalkylsulfinyl, C 1 -C 4 haloalkylsulfonyl, C 1 -C 4 alkylamino, C 2 -C 6 dialkylamino, piperidyl, Pyrrolidyl, N-methylpiperazinyl, morpholinyl, H(C═O), C 1 -C 4 alkylaminocarbonyl, C 1 -C 4 alkoxycarbonyl, C 1 -C 4 alkylaminothio, C 2 -C 4 dialkylaminothio, C 3 -C 6 cycloalkyl or R 8 ;

Y is selected from O, S or NR 7 ;

Z is O;

R 7 is selected from H, CN, NH 2 , OH, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 3 -C 6 cycloalkyl, C 1 -C 4 cyanoalkyl, C 1 -C 4 cyanoalkoxy, C 1 -C 4 alkylamino, C 1 -C 4 haloalkylamino, C 2 -C 4 dialkylamino, piperidyl, pyrrolidyl, N-methylpiperazinyl, morpholinyl, 2,6-dimethylmorpholinyl, C 2 -C 4 alkenyl, C 2 -C 4 haloalkenyl, C 2 -C 4 alkenoxy, C 2 -C 4 haloalkenoxy, C 2 -C 4 alkynyl, C 2 -C 4 haloalkynyl, C 2 -C 4 alkynoxy, C 2 -C 4 haloalkynoxy, C 1 -C 4 alkylthio, C 1 -C 4 haloalkylthio, C 1 -C 4 alkylsulfonyl, C 1 -C 4 haloalkylsulfonyl, C 1 -C 4 alkylcarbonyl, C 1 -C 4 haloalkylcarbonyl, C 1 -C 4 alkoxycarbonylC 1 -C 4 alkyl, C 1 -C 4 alkylcarbonylamino,

 or R 8 ;

Or, when Y is selected from NR 7 , NR 7 and R 5 form a unsubstituted or substituted five-membered or six-membered ring with 1-2 substitutents selected independently from C 1 -C 3 alkyl;

R 8 is selected from phenyl, benzoyl, phenoxycarbonyl, phenylaminocarbonyl, benzyl, phenethyl, naphthyl, pyridyl, picolyl, pyridylethyl, pyrimidyl, pyridazinyl, pyrazinyl, cyanuro, unsym-triazinyl, furanyl, thienyl, pyrrolyl, thiazolyl, pyrazolyl, imidazolyl, oxazolyl, isoxazolyl, thiadiazolyl, oxadizolyl, benzofuryl, benzothiophenyl, benzothiazolyl, benzoxazolyl, benzoxazolylmethyl, benzopyranyl, benzopyronyl, benzopyridazinyl, indolyl, quinolyl, quinoxalinyl, triazolopyrimidinyl, imidazopyridinyl, imidazothiazolyl, purinyl, pyridylformoxyl, pyrimidinylformoxyl, pyridyloxycarbonyl, pyrimidinyloxycarbonyl, pyridylaminocarbonyl, pyrimidinylaminocarbonyl or thiazolylmethyl, which can be unsubstituted or further substituted with 1-3 substitutents, the substitutent(s) mentioned was (were) selected independently from halogen, NO 2 , CN, SH, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 3 -C 6 cycloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 alkylthio, C 1 -C 4 haloalkylthio, C 2 -C 4 alkenyl, C 2 -C 4 haloalkenyl, C 2 -C 4 alkynyl, C 2 -C 4 haloalkynyl, C 3 -C 6 alkenoxy, C 3 -C 6 haloalkenoxy, C 3 -C 6 alkynoxy, C 3 -C 6 haloalkynoxy, C 1 -C 4 alkylsulfinyl, C 1 -C 4 haloalkylsulfinyl, C 1 -C 4 alkylsulfonyl, C 1 -C 4 haloalkylsulfonyl, C 1 -C 4 alkylcarbonyl, C 1 -C 4 haloalkylcarbonyl, C 1 -C 4 alkylcarbonyloxy, C 1 -C 4 alkylcarbonylamino, C 1 -C 4 alkylsulfonyloxy, C 1 -C 4 alkoxycarbonyl, C 1 -C 4 alkoxyC 1 -C 4 alkoxy, C 1 -C 4 alkoxycarbonylC 1 -C 4 alkyl, C 1 -C 4 alkoxycarbonylamino, C 1 -C 4 alkoxycarbonylC 1 -C 4 alkoxy, CHO, CO 2 H, CO 2 Na, CO 2 NH 4 , NR 9 R 10 , C(═O)NR 9 R 10 , OC(═O)NR 9 R 10 , C(═S)NR 9 R 10 or SO 2 NR 9 R 10 ;

R 9 and R 10 may be the same or different, mutually independently selected from H, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 alkylthio, C 1 -C 4 haloalkylthio, C 3 -C 6 cycloalkyl or R 8 ;

(CHR 3 )mCON(Q 2 ) links with phenyl ring at the 2, 3 or 4-position.

3. The compound according to claim 2 , wherein:

R 1 is selected from H, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxyC 1 -C 4 alkyl, C 3 -C 6 cycloalkyl or R 8 ;

R 2 is selected from H, chloride, bromine, fluorine, iodine, CN, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 cyanoalkoxy, C 1 -C 4 alkoxyC 1 -C 4 alkyl, C 1 -C 4 haloalkoxyC 1 -C 4 alkyl, C 3 -C 6 cycloalkyl or R 8 ;

R 3 is selected from H, methyl or ethyl; m is selected from 1, 2 or 3;

R 4 is selected from fluorine, chloride, bromine, iodine, CN, NO 2 , C 1 -C 3 alkyl, C 3 haloalkyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, C 1 -C 3 alkylamino, C 2 -C 4 dialkylamino or C 1 -C 3 alkylsulfonyl; n is selected from 0, 1, 2 or 3;

R 5 is selected from H, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxyC 1 -C 3 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 4 cyanoalkyl, C 1 -C 4 alkylamino, C 2 -C 6 dialkylamino, C 3 -C 4 alkenyl, C 3 -C 4 alkynyl or R 8 ;

R 6 is selected from H, CN, SCN, C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, C 1 -C 3 alkoxy, C 1 -C 3 alkylthio or C 1 -C 3 hydroxyalkyl; p is selected from 0, 1, 2 or 3;

X 1 is selected from H, fluorine, chloride, bromine, iodine, NO 2 , CN, SCN, C 1 -C 3 alkyl or C 1 -C 3 haloalkyl;

X 2 , X 3 , X 4 and X 5 may be the same or different, mutually independently selected from H, fluorine, chloride, bromine, iodine, CN, NO 2 , OH, C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, C 1 -C 3 alkoxy or C 1 -C 3 haloalkoxy;

Q 1 and Q 2 may be the same or different, mutually independently selected from H, CN, SCN, C 1 -C 3 alkyl, C 1 -C 3 alkylcarbonyl, C 1 -C 3 alkoxyC 1 -C 2 alkyl or H(C═O);

Y is selected from O or NR 7 ;

Z is O;

R 7 is selected from H, CN, NH 2 , OH, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy, C 3 -C 6 cycloalkyl, C 1 -C 3 cyanoalkyl, C 1 -C 3 cyanoalkoxy, C 1 -C 3 alkylamino, C 1 -C 3 haloalkylamino, C 2 -C 4 dialkylamino, piperidyl, pyrrolidyl, N-methylpiperazinyl, morpholinyl, 2,6-dimethylmorpholinyl, C 3 -C 4 alkenyl, C 3 -C 4 haloalkenyl, C 3 -C 4 alkenoxy, C 3 -C 4 haloalkenoxy, C 3 -C 4 alkynyl, C 3 -C 4 haloalkynyl, C 3 -C 4 alkynoxy, C 3 -C 4 haloalkynoxy, C 1 -C 3 alkylsulfonyl, C 1 -C 3 haloalkylsulfonyl or R 8 ;

Or, when Y is selected from NR 7 , NR 7 and R 5 form piperidine, tetrahydropyrrole, N-methylpiperazine, morpholine or 2,6-dimethylmorpholine;

R 8 is selected from phenyl, 4-chlorophenyl, 2,4-dichlorophenyl, 4-methylphenyl, trifluoromethylphenyl, 4-methoxylphenyl, 2,6-dichloro-4-trifluoromethylphenyl, benzoyl, 4-chlorobenzoyl, 2,4-dichlorobenzoyl, 4-trifluoromethylbenzoyl, phenoxycarbonyl, chlorophenoxycarbonyl, 2,4-dichlorophenoxycarbonyl, 4-trifluoromethylphenoxycarbonyl, phenylaminocarbonyl, 4-chlorophenylaminocarbonyl, 2,4-dichlorophenylaminocarbonyl, 4-trifluoromethyphenylaminocarbonyl, benzyl, 4-chlorobenzyl, 4-tert-butylbenzyl, 4-trifluoromethylbenzyl, phenethyl, 2-pyridyl, 3-chloro-2-pyridyl, 3,5-dichloro-2-pyridyl, 3,5,6-trichloro-2-pyridyl, 5-trifluoromethyl-2-pyridyl, 5-methyl-2-pyridyl, 3-chloro-5-cyano-2-pyridyl, 3-chloro-5-trifluoromethyl-2-pyridyl, 2-picolyl, 2-chloro-5-picolyl, 3-chloro-5-trifluoro-2-picolyl, 2-pyridinylethyl, 3-chloro-5-trifluoromethyl-2-pyridinylethyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl, thiazole-2-yl, 2-chloro-5-thiazolylmethyl, 3-pyridylformoxyl, 2-chloro-3-pyridylformoxyl, 2-chloro-5-pyridylformoxyl, 2-pyrimidinylformoxyl, 5-trifluoromethyl-2-pyrimidinylformoxyl, 2-pyridyloxycarbonyl, 3-chloro-2-pyridyloxycarbonyl, 3,5-dichloro-2-pyridyloxycarbonyl, 5-trifluoromethyl-2-pyridyloxycarbonyl, 5-methyl-2-pyridyloxycarbonyl, 3-chloro-5-cyano-2-pyridyloxycarbonyl, 3-chloro-5-trifluoromethyl-2-pyridyloxycarbonyl, 2-pyrimidinyloxycarbonyl, 5-trifluoromethyl-2-pyrimidinyloxycarbonyl, 2-pyridylaminocarbonyl, 3-chloro-2-pyridylaminocarbonyl or 2-pyrimidinylaminocarbonyl;

(CHR 3 )mCON(Q 2 ) links with phenyl ring at the 2, 3 or 4-position.

4. The compound according to claim 3 , wherein:

R 1 is selected from H, methyl, ethyl, n-propyl, isopropyl, n-butyl, s-butyl, isobutyl, t-butyl, trifluoromethyl, trifluoroethyl, methoxymethyl, ethoxymethyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl or R 8 ;

R 2 is selected from H, chloride, bromine, fluorine, CN, methyl, ethyl, n-propyl, i-propyl, n-butyl, s-butyl, i-butyl, t-butyl, trifluoromethyl, difluoromethyl, fluoromethyl, trifluoromethoxyl, trifluoroethoxyl, fluoromethoxyl, cyanomethoxyl, methoxymethyl, trifluoromethoxymethyl, trifluoroethoxymethyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl or R 8 ;

R 3 is selected from H or methyl; m is 1;

R 4 is selected from fluorine, chloride, bromine, iodine, CN, methyl, ethyl, trifluoromethyl, methoxyl, trifluoromethoxyl or methylsulfonyl; n is selected from 0, 1, 2 or 3;

R 5 is selected from H, methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, trifluoromethyl, trifluoroethyl, cyclopropyl, cyclohexyl, cyanomethyl, allyl, propargyl or R 8 ;

R 6 is selected from H, CN, SCN, methyl or ethyl; p is selected from 0, 1, 2 or 3;

X 1 is selected from H, fluorine, chloride, bromine, iodine, NO 2 , methyl or chloromethyl;

X 2 , X 3 , X 4 and X 5 may be the same or different, mutually independently selected from H, chloride, bromine or methoxyl;

Q 1 and Q 2 are H;

Y is selected from O or NR 7 ;

Z is O;

R 7 is selected from H, CN, NH 2 , OH, methyl, ethyl, cyclopropyl, cyclopentyl, cyclohexyl, cyanomethyl, methylamino, dimethylamino, methylsulfonyl or R 8 ;

Or, when Y is selected from NR 7 , NR 7 and R 5 form piperidine, tetrahydropyrrole, N-methylpiperazine, morpholine or 2,6-dimethylmorpholine;

R 8 is selected from phenyl, 4-chlorophenyl, 2,4-dichlorophenyl, 4-methylphenyl, 4-trifluoromethylphenyl, 4-methoxylphenyl, 2,6-dichloro-4-trifluoromethylphenyl, benzyl, 4-chlorobenzyl, 4-tert-butylbenzyl, 4-trifluoromethylbenzyl, phenethyl, 2-pyridyl, 3-chloro-2-pyridyl, 3,5-dichloro-2-pyridyl, 3,5,6-trichloro-2-pyridyl, 5-trifluoromethyl-2-pyridyl, 5-methyl-2-pyridyl, 3-chloro-5-cyano-2-pyridyl, 3-chloro-5-trifluoromethyl-2-pyridyl, 2-picolyl, 2-chloro-5-picolyl, 3-chloro-5-trifluoromethyl-2-picolyl, 2-pyridinylethyl, 3-chloro-5-trifluoromethyl-2-pyridinylethyl, thiazole-2-yl, 2-chloro-5-thiazolylmethyl or 2-pyrimidinyl;

(CHR 3 )mCON(Q 2 ) links with phenyl ring at the 2, 3 or 4-position.

5. The compound according to claim 4 , wherein:

R 2 is selected from bromine, methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, trifluoromethyl, cyclopropyl or 4-chlorophenyl;

R 3 is selected from H or methyl; m is 1;

R 4 is selected from fluorine, chloride, bromine, iodine, CN or methyl; n is selected from 0, 1 or 2;

R 6 is selected from H or methyl; p is selected from 0, 1, 2 or 3;

X 1 is selected from H, chloride or methyl;

X 2 , X 3 , X 4 , X 5 , Q 1 , Q 2 are H;

Z is O;

YR 5 is selected from amino, methylamino, ethylamino, dimethylamino, methoxyl, ethoxyl or morpholinyl;

(CHR 3 )mCON(Q 2 ) links with phenyl ring at the 2, 3 or 4-position.

6. A method of preparation of a compound of general formula (I) (when Q 1 =H) according to claim 1 , according to the following reaction routes:

Wherein:

R 1 is selected from H, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkoxycarbonyl, C 1 -C 12 haloalkoxycarbonyl, C 1 -C 12 alkylaminocarbonyl, C 1 -C 12 haloalkylaminocarbonyl, C 3 -C 6 cycloalkyl or R 8 ;

R 2 is selected from H, halogen, CN, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 cyanoalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 haloalkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylthioC 1 -C 12 alkyl, C 1 -C 12 haloalkylthioC 1 -C 12 alkyl, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 3 -C 6 cycloalkyl or R 8 ;

R 3 is selected from H or C 1 -C 12 alkyl; m is selected from 0 to 5;

R 4 is selected from halogen, CN, CONH 2 , CSNH 2 , NO 2 , C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 haloalkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylthioC 1 -C 12 alkyl, C 1 -C 12 haloalkylthioC 1 -C 12 alkyl, C 1 -C 12 alkylamino, C 1 -C 12 haloalkylamino, C 2 -C 12 dialkylamino, piperidyl, pyrrolidyl, N-methyl piperazinyl, morpholinyl, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkenoxy, C 2 -C 12 haloalkenoxy, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 2 -C 12 alkynoxy, C 2 -C 12 haloalkynoxy, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl or R 8 ; n is selected from 0 to 4;

R 5 is selected from H, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkylamino, C 1 -C 12 haloalkylamino, C 2 -C 12 dialkylamino, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylcarbonylamino,

 or R 8 ;

R 6 is selected from H, CN, SCN, H(C═O), C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkylcarbonyl, C 1 -C 12 alkoxycarbonyl, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 hydroxyalkyl, C 3 -C 6 cycloalkyl or R 8 ; p is selected from 0 to 5;

X 1 is selected from H, halogen, NO 2 , CN, SCN, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfinyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 haloalkylthio, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 haloalkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylthioC 1 -C 12 alkyl or C 1 -C 12 haloalkylthioC 1 -C 12 alkyl;

X 2 , X 3 , X 4 and X 5 may be the same or different, mutually independently selected from H, halogen, CN, NO 2 , OH, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio or C 1 -C 12 alkylsulfonyl;

Q 2 is selected from H, NH 2 , OH, CN, SCN, C 1 -C 12 cyanoalkyl, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkoxyC 1 -C 12 alkyl, C 1 -C 12 alkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfinyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylamino, C 2 -C 12 dialkylamino, piperidyl, pyrrolidyl, N-methyl piperazinyl, morpholinyl, H(C═O), C 1 -C 12 alkylaminocarbonyl, C 1 -C 12 alkoxycarbonyl, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylaminothio, C 2 -C 12 dialkylaminothio, C 3 -C 6 cycloalkyl or R 8 ;

Y is selected from O, S or NR 7 ;

Z is selected from O or S;

R 7 is selected from H, CN, NH 2 , OH, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 3 -C 6 cycloalkyl, C 1 -C 12 cyanoalkyl, C 1 -C 12 cyanoalkoxy, C 1 -C 12 alkylamino, C 1 -C 12 haloalkylamino, C 2 -C 12 dialkylamino, piperidyl, Pyrrolidyl, N-methylpiperazinyl, morpholinyl, 2,6-dimethylmorpholinyl, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkenoxy, C 2 -C 12 haloalkenoxy, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 2 -C 12 alkynoxy, C 2 -C 12 haloalkynoxy,

C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkylcarbonylamino,

 or R 8 ;

Or, when Y is selected from NR 7 , NR 7 and R 5 form a unsubstituted or substituted five-membered or six-membered ring with 1-4 substitutents selected independently from C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkoxy or C 3 -C 6 cycloalkyl;

R 8 is selected from phenyl, benzoyl, phenoxycarbonyl, phenylaminocarbonyl, phenylC 1 -C 6 alkyl, naphthyl, naphthylC 1 -C 6 alkyl, heteroaryl, heteroarylcarbonyl, heteroaryloxycarbonyl, heteroarylaminocarbonyl or heteroarylC 1 -C 6 alkyl, which can be unsubstituted or further substituted with 1-5 substitutents, the substitutent(s) mentioned was (were) selected independently from halogen, NO 2 , CN, SH, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 3 -C 12 cycloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 2 -C 12 alkenyl, C 2 -C 12 haloalkenyl, C 2 -C 12 alkynyl, C 2 -C 12 haloalkynyl, C 3 -C 12 alkenoxy, C 3 -C 12 haloalkenoxy, C 3 -C 12 alkynoxy, C 3 -C 12 haloalkynoxy, C 1 -C 1 -C 12 haloalkylsulfinyl, C 1 -C 12 alkylsulfonyl, C 1 -C 12 haloalkylsulfonyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 haloalkylcarbonyl, C 1 -C 12 alkylcarbonyloxy, C 1 -C 12 alkylcarbonylamino, C 1 -C 12 alkylsulfonyloxy, C 1 -C 12 alkoxycarbonyl, C 1 -C 12 alkoxyC 1 -C 12 alkoxy, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkyl, C 1 -C 12 alkoxycarbonylamino, C 1 -C 12 alkoxycarbonylC 1 -C 12 alkoxy, CHO, CO 2 H, CO 2 Na, CO 2 NH 4 , NR 9 R 10 , C(═O)NR 9 R 10 , OC(═O)NR 9 R 10 , C(═S)NR 9 R 10 or SO 2 NR 9 R 10 ;

R 9 and R 10 may be the same or different, mutually independently selected from H, C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy, C 1 -C 12 haloalkoxy, C 1 -C 12 alkylthio, C 1 -C 12 haloalkylthio, C 3 -C 6 cycloalkyl or R 8 ;

(CHR 3 )mCON(Q 2 ) links with phenyl ring at the 2, 3 or 4-position.

7. A method of controlling fungi which comprises applying the compound having general formula (I) according to claim 1 to agricultural fields.

8. A fungicidal composition comprising the compound having general formula (I) of claim 1 as an active ingredient, wherein the weight percentage of the active ingredient in the composition is from 0.1-99%.

9. A method of controlling fungi which comprises applying the composition according to claim 8 to agricultural fields.

10. A method of controlling fungi which comprises applying the compound having general formula (I) according to claim 2 to agricultural fields.

11. A fungicidal composition comprising the compound having general formula (I) of claim 2 as an active ingredient, wherein the weight percentage of the active ingredient in the composition is from 0.1-99%.

12. A method of controlling fungi which comprises applying the composition according to claim 11 to agricultural fields.

13. A method of controlling fungi which comprises applying the compound having general formula (I) according to claim 3 to agricultural fields.

14. A fungicidal composition comprising the compound having general formula (I) of claim 3 as an active ingredient, wherein the weight percentage of the active ingredient in the composition is from 0.1-99%.

15. A method of controlling fungi which comprises applying the composition according to claim 14 to agricultural fields.

16. A method of controlling fungi which comprises applying the compound having general formula (I) according to claim 4 to agricultural fields.

17. A fungicidal composition comprising the compound having general formula (I) of claim 4 as an active ingredient, wherein the weight percentage of the active ingredient in the composition is from 0.1-99%.

18. A method of controlling fungi which comprises applying the composition according to claim 17 to agricultural fields.

19. A method of controlling fungi which comprises applying the compound having general formula (I) according to claim 5 to agricultural fields.

20. A fungicidal composition comprising the compound having general formula (I) of claim 5 as an active ingredient, wherein the weight percentage of the active ingredient in the composition is from 0.1-99%.

21. A method of controlling fungi which comprises applying the composition according to claim 20 to agricultural fields.