IP Library › Granted Patent US 8,623,913
Granted Patent B2
US 8,623,913 · App. 12/827,529 · Granted Jan 7, 2014

Methods for treating restless legs syndrome

Inventors: Susan Marie Melnick (Parsippany, NJ); Duncan Paul Taylor (Flemington, NJ)
Assignee: SK Biopharmaceuticals Co., Ltd.
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Quick Facts
Patent No.
US 8,623,913
App. No.
12/827,529
Granted
Jan 7, 2014
Kind
B2
Abstract

The invention is directed to a method of treating restless legs syndrome in a subject, comprising administering a therapeutically effective amount of a carbamate compound, or pharmaceutically acceptable salt or amide thereof.

Claims (10)

1. A method of treating restless legs syndrome, comprising the administration of a therapeutically effective amount of a compound having structural Formula (1) or a pharmaceutically acceptable salt or amide thereof, to a mammal in need of treatment:

wherein,

R 1 and R 2 are hydrogen and

the compound of structural Formula (1) is an enantiomeric mixture wherein the (R) enantiomer of the compound predominates.

2. The method of claim 1 , wherein the (R) enantiomer predominates to the extent of about 90% or greater.

3. The method of claim 2 , wherein the (R) enantiomer predominates to the extent of about 98% or greater.

4. A method of treating restless legs syndrome comprising the administration of a therapeutically effective amount of a compound having structural Formula (1) or a pharmaceutically acceptable salt thereof, to a mammal in need of treatment:

wherein,

R 1 and R 2 are hydrogen; and

the compound of structural Formula (1) is the (R) enantiomer substantially free of other enantiomers.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE MAILING ADDRESS COUNTRY OF THE ASSIGNEE PREVIOUSLY RECORDED ON REEL 026892 FRAME 0846. ASSIGNOR(S) HEREBY CONFIRMS THE MAILING ADDRESS COUNTRY OF THE ASSIGNEE SHOULD BE CHANGED FROM "KOREA, DEMOCRATIC PEOPLE'S REPUBLIC OF" TO "KOREA, REPUBLIC OF". Recorded Nov 6, 2013
From: SK HOLDINGS CO., LTD.
To: SK BIOPHARMACEUTICALS CO., LTD.
Reel/Frame 031589/0390 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 13, 2011
From: SK HOLDINGS CO., LTD.
To: SK BIOPHARMACEUTICALS CO., LTD.
Reel/Frame 026892/0846 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 30, 2010
From: MELNICK, SUSAN MARIE; TAYLOR, DUNCAN PAUL
To: SK HOLDINGS CO., LTD.
Reel/Frame 024619/0270 →
Continuity (1)
Related Publication 20120004301A1 · Jan 5, 2012