IP Library Granted Patent US 8,672,219
Granted Patent B2
US 8,672,219 · App. 13/596,199 · Granted Mar 18, 2014

Handling of sample tubes comprising geometric tube data

Inventor: Frederic Furrer (Horw, CH)
Assignee: Roche Diagnostics Operations, Inc.
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Quick Facts
Patent No.
US 8,672,219
App. No.
13/596,199
Granted
Mar 18, 2014
Kind
B2
Abstract

A method for handling a sample tube containing a biological sample is presented. A tube label can be attached to the sample tube. The tube label can carry tube data. The tube data can comprise at least geometric tube data descriptive of at least one geometric property of the sample tube. At least the geometric tube data can be read from the tube label by a reader device. At least the geometric tube data from the reader device can be transmitted to a processing device. The processing device for handling the sample tube can be controlled in accordance with the at least one geometric property described by the read geometric data.

Claims (41)

1. A method for handling a sample tube containing a biological sample, a tube label being attached to the sample tube, the tube label carrying tube data, the tube data comprising at least geometric tube data being descriptive of at least one geometric property of the sample tube, the method comprising:

reading at least the geometric tube data from the tube label by a reader device;

transmitting at least the geometric tube data from the reader device to a processing device;

controlling the processing device for handling the sample tube in accordance with the at least one geometric property described by the read geometric data;

determining the approximate weight of an empty sample tube by using the read geometric properties or by reading the weight of an empty sample tube from the tube label by the reader device;

weighing the sample tube containing the biological sample;

determining the weight difference between the empty sample tube and the sample tube containing the biological sample; and

determining the filling level of the sample tube using the weight difference and the geometric properties.

2. The method of claim 1 , wherein the tube data comprising one or more of the following geometric properties of the sample tube: outer tube diameter, inner tube diameter, tube length, diameter of tube cap, free height of tube cap, location and/or shape of a false bottom.

3. The method of claim 1 , wherein the processing device comprising a gripper, wherein the gripper has an opening position for receiving or releasing the sample tube or a cap of the sample tube and a gripping position for gripping the sample tube or cap of the sample tube, wherein at least the gripping position is adjusted depending on the at least one geometric property.

4. The method of claim 1 , wherein the processing device is a de-capper or a re-capper comprising a tube gripper and a cap gripper, wherein the tube gripper is controlled depending on the geometric property of the sample tube's shape and the cap gripper is controlled in accordance with a geometric property of the tube cap.

5. The method of claim 1 , wherein the sample tube has a screw cap, wherein the tube data comprise tube cap data being indicative of the number of turns that are required to take the screw cap off the sample tube, the processing device being a de-capper comprising a cap gripper, wherein the cap gripper is controlled for turning the screw cap the number of turns as indicated by the read tube cap data.

6. The method of claim 1 , wherein the reader device is an optical reader.

7. The method of claim 1 , wherein the reader device is an RFID reader.

8. The method of claim 1 , wherein the tube label comprises an optically readable pattern.

9. The method of claim 8 , wherein the optically readable pattern is a barcode.

10. The method of claim 9 , wherein the barcode is a two-dimensional bar code.

11. The method of claim 1 , further comprising,

attaching an antenna to the sample tube, wherein the tube label comprises a sender for sending the tube data via the antenna.

12. The method of claim 11 , wherein the tube label comprises an RFID circuit.

13. The method of claim 12 , wherein the RFID circuit is a printed polymer electronic circuit.

14. The method of claim 1 , wherein a plurality of the sample tubes are handled by the processing device, the at least one geometric property of each one of the sample tube tubes having any value within a processing range for the processing device irrespective of sample tube types.

15. The method of claim 1 , wherein the tube data comprising one or more of the following geometric properties of the sample tube: inner tube diameter, diameter of tube cap, free height of tube cap, location and/or shape of a false bottom.

16. A sample tube, the sample tube comprising:

a tube label, wherein the tube label carries tube data, the tube data comprising at least geometric tube data being descriptive of at least one geometric property of the sample tube and of geometric properties of the tube cap.

17. A system for processing sample tubes, the sample tubes containing biological samples, at least one of the sample tubes having a tube label attached to the sample tube, the tube label carrying tube data, the tube data comprising at least geometric tube data being descriptive of at least one geometric property of the sample tube, the system comprising:

a reader device for reading at least the geometric tube data from the tube label; and

a processing device for handling the sample tubes, the processing device comprising a controller, wherein the reader device is coupled to the processing device for entering the geometric tube data into the controller, wherein the controller is operable to control the processing device in dependence on the geometric tube data, and wherein the processing device is an automated centrifuge comprising a loading station for loading sample tubes into the centrifuge, the loading station comprising a gripper, the gripper being controlled for placing the sample tube into a centrifugation bucket depending on the read geometric tube data, whereby the geometric data is used for determining the volume and/or weight of the loaded samples and wherein the determined volume or weight is used for loading samples of approximately equal weight or of approximately equal volume into centrifuge buckets lying oppositely to each other.

18. The system of claim 17 , further comprising,

the sample tubes, wherein each of the sample tubes has attached the tube label, the tube label carrying tube data, the tube data of each sample tube comprising at least the geometric tube data being descriptive of at least one geometric property of the sample tube.

19. A method for handling a sample tube containing a biological sample, a tube label being attached to the sample tube, the tube label carrying tube data, the tube data comprising at least geometric tube data being descriptive of interior geometric properties of the sample tube and of geometric properties of the tube cap, the method comprising:

reading at least the geometric tube data from the tube label by a reader device;

transmitting at least the geometric tube data from the reader device to a processing device;

controlling the processing device for handling the sample tube in accordance with the interior geometric properties of the sample tube and with the geometric properties of the tube cap described by the read geometric data

determining the approximate weight of an empty sample tube by using the read geometric properties or by reading the weight of an empty sample tube from the tube label by the reader device:

weighing the sample tube containing the biological sample;

determining the weight difference between the empty sample tube and the sample tube containing the biological sample; and

determining the filling level of the sample tube using the weight difference and the geometric properties.

20. A system for processing sample tubes, the sample tubes containing biological samples, at least one of the sample tubes having a tube label attached to the sample tube, the tube label carrying tube data, the tube data comprising at least geometric tube data being descriptive of interior geometric properties of the sample tube and of geometric properties of the tube cap, the system comprising:

a reader device for reading at least the geometric tube data from the tube label; and

a processing device for handling the sample tubes, the processing device comprising a controller, wherein the reader device is coupled to the processing device for entering the geometric tube data into the controller, wherein the controller is operable to control the processing device in dependence on the of interior geometric properties of the sample tube and of geometric properties of the tube cap, and wherein the processing device is an automated centrifuge comprising a loading station for loading sample tubes into the centrifuge, the loading station comprising a gripper, the gripper being controlled for placing the sample tube into a centrifugation bucket depending on the read geometric tube data, whereby the geometric data is used for determining the volume and/or weight of the loaded samples and wherein the determined volume or weight is used for loading samples of approximately equal weight or of approximately equal volume into centrifuge buckets lying oppositely to each other.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2012
From: FURRER, FREDERIC
To: ROCHE DIAGNOSTICS INTERNATIONAL AG
Reel/Frame 028898/0476 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2012
From: ROCHE DIAGNOSTICS INTERNATIONAL AG
To: ROCHE DIAGNOSTICS OPERATIONS, INC.
Reel/Frame 028898/0488 →
Priority Claims (1)
EP 11183365 · Sep 29, 2011 · regional
Continuity (1)
Related Publication 20130082099A1 · Apr 4, 2013