IP Library › Granted Patent US 8,703,920
Granted Patent B2
US 8,703,920 · App. 12/590,601 · Granted Apr 22, 2014

Fully human antibodies against N-cadherin

Inventors: Robert E. Reiter (Los Angeles, CA); Eric Lepin (Los Angeles, CA); Anna M. Wu (Sherman Oaks, CA)
Assignee: The Regents of the University of California
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Quick Facts
Patent No.
US 8,703,920
App. No.
12/590,601
Granted
Apr 22, 2014
Kind
B2
Abstract

The present application provides fully human antibodies against N-Cadherin for therapeutic and diagnostic methods in cancer.

Claims (3)

1. A monoclonal antibody or fragment thereof comprising the amino acid sequence of SEQ ID NO:1, wherein the antibody or fragment thereof is capable of binding to extracellular domain 4 of N-cadherin.

2. The antibody of claim 1 , wherein the fragment is a scFv.

3. The antibody of claim 1 , wherein the fragment is a diabody.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 19, 2010
From: REITER, ROBERT E.; LEPIN, ERIC; WU, ANNA M.
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 023812/0896 →
CONFIRMATORY LICENSE Recorded Dec 23, 2009
From: UNIVERSITY OF CALIFORNIA LOS ANGELES
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 023698/0449 →
Continuity (2)
Provisional Application 61113042 · Nov 10, 2008
Related Publication 20100233170A1 · Sep 16, 2010