IP Library › Granted Patent US 8,703,942
Granted Patent B2
US 8,703,942 · App. 12/939,807 · Granted Apr 22, 2014

Small-molecule Hsp90 inhibitors

Inventors: Gabriela Chiosis (New York, NY); Huazhong He (New York, NY); Laura Llauger-Bufi (New York, NY); Joungnam Kim (Forest Hills, NY); Steve M. Larson (New York, NY); Peter Smith-Jones (New York, NY)
Assignee: Sloan-Kettering Institute for Cancer Research
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Quick Facts
Patent No.
US 8,703,942
App. No.
12/939,807
Granted
Apr 22, 2014
Kind
B2
Abstract

The present disclosure provides inhibitors of Hsp90 and methods of making and using the same. Such compounds are useful as radioimaging ligands and for the treatment of cancer and other conditions where cell growth or maintenance depend on Hsp90 activity.

Claims (1)

1. An acid addition salt of the compound:

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF INVENTOR 2 HUAZHONG HE PREVIOUSLY RECORDED ON REEL 030982 FRAME 0508. ASSIGNOR(S) HEREBY CONFIRMS THE NAME OF INVENTOR 2 HUAZHONG HE IS NOW CORRECT. Recorded Jul 23, 2020
From: CHIOSIS, GABRIELA; HE, HUAZHONG; LLAUGER-BUFI, LAURA; KIM, JOUNGNAM; LARSON, STEVE M; SMITH-JONES, PETER
To: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
Reel/Frame 053298/0167 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2013
From: CHIOSIS, GABRIELA; HUAZHONG, HE; LLAUGER-BUFI, LAURA; KIM, JOUNGNAM; LARSON, STEVE M.; SMITH-JONES, PETER
To: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
Reel/Frame 030982/0508 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 19, 2011
From: CHIOSIS, GABRIELA; HE, HUAZHONG; LLAUGER-BUFI, LAURA; KIM, JOUNGNAM; LARSON, STEVE M.; SMITH-JONES, PETER
To: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
Reel/Frame 025658/0481 →
Continuity (3)
Continuation 11814506
Provisional Application 60649322 · Feb 1, 2005
Related Publication 20110104054A1 · May 5, 2011