Compositions for the targetted release of fragrances and aromas
In a fragrance and/or aroma composition for the targeted release of fragrances and/or aromas in the form of a solid lipid nanoparticle (SLN) dispersion, in which lipid-based nanoparticles are present which are stabilized by an emulsifier monolayer, one or more membrane layers or other auxiliaries, the fragrances and/or aromas are included in the nanoparticles and/or in the emulsifier monolayer or the membrane layers.
1. A method of preparing a solid lipid nanoparticle (SLN) dispersion for the targeted release of fragrances and/or aromas, the method comprising the steps of:
a) mixing the fragrance and/or aroma with the lipid-based active ingredient carrier and at least one emulsifier, which leads, in stage b), to the formation of a lyotropic lamellar liquid-crystalline mixed phase, at a temperature above the melting or softening point of the active ingredient carrier, to form a phase B,
b) mechanical mixing, without high-pressure homogenization, of the phase B with an aqueous phase or polyol phase A at a temperature that is above the melting or softening point of the active ingredient carrier and is up to 70 degrees Celsius, where the weight ratio of phase B to phase A is 1:5 to 5:1 to form a lyotropic lamellar liquid-crystalline mixed phase,
c) diluting the mixed phase with an aqueous phase or polyol phase at a temperature of the aqueous phase or polyol phase below the melting or softening point of the active ingredient carrier by stirring without high-pressure homogenization to produce a desired end concentration of the dispersion, the dispersion containing lipid-based nanoparticles stabilized by an emulsifier monolayer or one or more membrane layers, the fragrances and/or aromas being included in the nanoparticles and/or in the emulsifier monolayer or the membrane layers and the dispersion being free of fragrance and/or aroma droplets.
2. The method according to claim 1 , wherein the aqueous phase or the polyol phase A in step b) comprises an emulsifier.
3. The method according to claim 1 , wherein the aqueous phase or the polyol phase A in step c) comprises an emulsifier.
4. The method according to claim 1 , wherein the aqueous phase or the polyol phase A in step b) and in step c) comprises an emulsifier.
5. The method according to claim 1 , wherein in step b) mixing is performed with a peripheral speed of a stirrer in the range of 1 m/s to 20 m/s.
6. The method according to claim 1 , wherein in step c) stirring is performed with a peripheral speed by a stirrer in the range of 1 m/s to 20 m/s.
7. A composition for the targeted release of fragrances and/or aromas, prepared by the method of claim 1 in the form of a cosmetic, pharmaceutical, food or detergent composition.
8. The composition according to claim 7 , wherein the fragrance and/or aroma is deposited at an interface of the lyotropic lamellar liquid crystalline phase with the highest absorbancy.