PTFE composite multi-layer material
View Patent ↗A composite multi-layer material may generally comprise a d-PTFE material combined with an open structured material (either resorbable or non-resorbable) creating a composite multi-layer material. Attachment of the layers may be accomplished by stitching layers of material, exertion of hydraulic or other pressure, application of a biocompatible adhesive or heat, or some combination of the foregoing. Use of a d-PTFE, unexpanded material has multiple alternative uses, including without limitation, placement on the visceral side of a hernia that may minimize or even eliminate the incidence of abdominal adhesions. Alternatively, the material may be used to create tubing sufficient as a graft for treating abdominal aortic aneurysms.
1. A method of treating a patient in need of tissue repair, comprising contacting the tissue in need of repair with a composite multi-layer material comprising:
a first layer formed from unsintered substantially unexpanded polytetrafluoroethylene polymer and having a density in a range of about 1.2 gm/cc to about 2.3 gm/cc and having a plurality of pores having a nominal channel size of less than 5 micrometers; and
a second layer formed from an open structured material, wherein surfaces of the first and second layers are attached at a common interface, wherein the first and second layers are attached by stitching at least a portion of said first layer to at least a portion of said second layer.
2. The method of claim 1 , wherein the nominal channel size is less than 2 micrometers.
3. The method of claim 1 , wherein the nominal channel size is less than 0.5 micrometers.
4. The method of claim 1 , wherein the nominal channel size is less than 0.2 micrometers.
5. The method of claim 1 , wherein the first layer has a hydrophobic surface.
6. The method of claim 1 , wherein the first layer has a hydrophilic surface.
7. The method of claim 1 , wherein the open structured material includes unexpanded PTFE.
8. The method of claim 7 , wherein the open structured material forms a non-woven flatsheet.
9. The method of claim 7 , wherein the open structured material forms a woven flatsheet.
10. The method of claim 7 , wherein the open structured material forms a mesh.
11. The method of claim 1 , wherein the open structured material includes polypropylene.
12. The method of claim 11 , wherein the open structured material forms a non-woven flatsheet.
13. The method of claim 11 , wherein the open structured material forms a woven flatsheet.
14. The method of claim 11 , wherein the open structured material forms a mesh.
15. The method of claim 11 , wherein the open structured material includes a resorbable polymer.
16. The method of claim 15 , wherein the open structured material forms a non-woven flatsheet.
17. The method of claim 15 , wherein the open structured material forms a woven flatsheet.
18. The method of claim 15 , wherein the open structured material forms a mesh.
19. The method of claim 1 , wherein the open structured material comprises a non-resorbable polymer.
20. The method of claim 19 , wherein the open structured material forms a non-woven flatsheet.
21. The method of claim 19 , wherein the open structured material forms a woven flatsheet.
22. The method of claim 19 , wherein the open structured material forms a mesh.
23. The method of claim 1 , wherein the first and second layers are attached using a biocompatible adhesive.
24. The method of claim 1 , wherein the first and second layers are attached using heat.
25. The method of claim 1 , wherein said composite multi-layer material forms a tube structure wherein said first layer forms the tube's interior surface and said second layer forms the tube's exterior surface.
26. The method of claim 1 , wherein the polytetrafluoroethylene polymer of the first layer has a density in the range of 1.45 gm/cc to 1.55 gm/cc.
27. The method of claim 1 , wherein the tissue in need of repair comprises a hernia.