IP Library Granted Patent US 8,754,126
Granted Patent B2
US 8,754,126 · App. 13/333,943 · Granted Jun 17, 2014

Methods for improving tolerance, digestion, and lipid soluble nutrient absorption in an infant, toddler, or child

Inventors: Chron-Si Lai (Blacklick, OH); Keith A. Garleb (Pickerington, OH); John B. Lasekan (Columbus, OH); Steven R. Davis (Columbus, OH); Christopher T. Cordle (Centerburg, OH); Russell J. Merritt (Columbus, OH)
Assignee: Abbott Laboratories
A23L1/296A23L1/3008
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Quick Facts
Patent No.
US 8,754,126
App. No.
13/333,943
Granted
Jun 17, 2014
Kind
B2
Abstract

Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component.

Claims (19)

1. A method for improving tolerance of an infant, toddler, or child, the method comprising administering to the infant, toddler or child a nutritional product comprising at least 0.2 wt % of total dry matter of at least one of a free fatty acid component and fatty acid-containing monoglycerides, wherein at least 70% of the fatty acids in the fatty acid-containing monoglycerides are at the Sn-1 position.

2. The method of claim 1 , wherein the fatty acid-containing monoglycerides are monoglycerol palmitate.

3. The method of claim 1 , wherein the free fatty acid component is in a form selected from the group consisting of calcium fatty acid salts, magnesium fatty acid salts, and combinations thereof.

4. The method of claim 1 , wherein the free fatty acid component comprises less than 15 wt % saturated fatty acids with a chain length of longer than 14 carbon atoms.

5. The method of claim 1 , wherein the free fatty acid component is derived from a vegetable oil.

6. The method of claim 5 , wherein the vegetable oil is selected from the group consisting of olive oil, canola oil, corn oil, soybean oil, and combinations thereof.

7. The method of claim 6 , wherein the vegetable oil is soybean oil.

8. The method of claim 1 , wherein the free fatty acid component is derived from fractionated animal fat having less than 20% (by weight) total myristic acid, palmitic acid, and stearic acid.

9. The method of claim 8 , wherein the free fatty acid component is derived from fractionated animal fat having less than 2% (by weight) total myristic acid, palmitic acid, and stearic acid.

10. The method of claim 5 , wherein the vegetable oil comprises less than 20% (by weight) total myristic acid, palmitic acid, and stearic acid.

11. The method of claim 1 , wherein the fatty acid-containing monoglycerides are derived by enzymatic hydrolysis of lard, tallow, or combinations thereof.

12. The method of claim 1 , wherein the nutritional product is free of carrageenan.

13. A method for improving digestion in an infant, toddler, or child, the method comprising administering to the infant, toddler or child a nutritional product comprising at least 0.2 wt % of total dry matter of at least one of a free fatty acid component and fatty acid-containing monoglycerides, wherein at least 70% of the fatty acids in the fatty acid-containing monoglycerides are at the Sn-1 position.

14. The method of claim 13 , wherein the fatty acid-containing monoglycerides are monoglycerol palmitate.

15. The method of claim 13 , wherein the free fatty acid component is in a form selected from the group consisting of calcium fatty acid salts, magnesium fatty acid salts, and combinations thereof.

16. The method of claim 13 , wherein the free fatty acid component comprises less than 15 wt % saturated fatty acids with a chain length of longer than 14 carbon atoms.

17. The method of claim 13 , wherein the free fatty acid component is derived from a vegetable oil.

18. The method of claim 17 , wherein the vegetable oil is selected from the group consisting of olive oil, canola oil, corn oil, soybean oil, and combinations thereof.

19. The method of claim 18 , wherein the vegetable oil is soybean oil.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 24, 2012
From: LAI, CHRON-SI; GARLEB, KEITH A.; LASEKAN, JOHN B.; DAVIS, STEVEN R.; CORDLE, CHRISTOPHER T.; MERRITT, RUSSELL J.
To: ABBOTT LABORATORIES
Reel/Frame 027758/0646 →
Continuity (6)
Provisional Application 61428168 · Dec 29, 2010
Provisional Application 61428173 · Dec 29, 2010
Provisional Application 61428176 · Dec 29, 2010
Provisional Application 61428177 · Dec 29, 2010
Provisional Application 61428185 · Dec 29, 2010
Related Publication 20120172434A1 · Jul 5, 2012