Cross-linkable polymeric compositions
A class of bioinspired, cross linking polymers, created by working catechol functionalities into the backbone of a bulk polymer, is disclosed. Varied cross linking groups may be incorporated into different polymer backbones, and subsequently reacted with an array of reagents. An adhesive composition comprising a copolymer, the copolymer comprising pendant dihydroxyphenyl groups; and a crosslinking agent selected from the group consisting of, for example, oxidants, enzymes, metals, and light. A method of preparing an adhesive composition comprising copolymerizing a first monomer comprising pendant dihydroxy-protected dihydroxyphenyl groups; deprotecting the dihydroxy-protected dihydroxyphenyl groups; crosslinking the dihydroxyphenyl groups with a crosslinking agent.
1. A cross-linkable polymeric composition comprising:
a polymer comprising at least two types of monomers, wherein at least one monomer is styrene and at least one monomer is a cross-linking group, wherein the at least one cross-linking group is 3,4-dihydroxystyrene;
wherein the ratio of 3,4-dihydroxystyrene to styrene is from about 1:15 to about 1:5;
wherein the polymer is a random polymer; and
wherein the at least one cross-linking group is able to cross-link with a cross-linking agent to form a composition having adhesive properties.
2. The cross-linkable polymeric composition of claim 1 , wherein another of the at least two types of monomers is selected from the group consisting of styrenesulfonate, ethylene, ethylene glycol, methylmethacrylate, acrylic acid, lactic acid and glycolic acid.
3. The cross-linkable polymeric composition of claim 1 , wherein the polymer is poly[styrene-co-(3,4-dihydroxystyrene)].
4. The cross-linkable polymeric composition of claim 1 , wherein the polymer is poly[styrene-co-dihydroxystyrene-co-styrenesulfonate].
5. The cross-linkable polymeric composition of claim 1 , wherein the cross-linking group is protected by a protecting group.
6. The cross-linkable polymeric composition of claim 1 , wherein the cross-linking agent is a metal or an oxidant.
7. The cross-linkable polymeric composition of claim 1 , wherein the polymer further comprises a third monomer, the third monomer being
8. The cross-linkable polymeric composition of claim 1 , wherein the polymer further comprises a third monomer, the third monomer being
9. The cross-linkable polymeric composition of claim 1 , wherein the polymer is able to cross-link with an oxidizing reagent to form a composition having adhesive properties.
10. The cross-linkable polymeric composition of claim 9 , wherein the oxidizing reagent is selected from the group consisting of [(C 4 H 9 ) 4 N]IO 4 , Fe(acetonylacetonate) 3 , [(C 4 H 9 ) 4 N](MnO 4 ), Mn(OOCCH 3 ) 3 , [(C 4 H 9 ) 4 N] 2 (Cr 2 O 7 ), Na 3 VO 4 [(C 4 H 9 ) 4 N] 3 , V 3 O 9 , and combinations thereof.
11. The cross-linkable polymeric composition of claim 10 , wherein the oxidizing reagent is [(C 4 H 9 ) 4 N](MnO 4 ).
12. The cross-linkable polymeric composition of claim 10 , wherein the oxidizing reagent is [(C 4 H 9 ) 4 N] 2 (Cr 2 O 7 ).
13. The cross-linkable polymeric composition of claim 10 , wherein the oxidizing reagent is [(C 4 H 9 ) 4 N] 3 V 3 O 9 .
14. The cross-linkable polymeric composition of claim 10 , wherein the oxidizing reagent is [(C 4 H 9 ) 4 N]IO 4 .