IP Library › Granted Patent US 8,765,453
Granted Patent B2
US 8,765,453 · App. 13/330,472 · Granted Jul 1, 2014

Automatic sample staining system

Inventors: Shazi S Iqbal (Danville, CA); Steven M Montgomery (Los Angeles, CA); Ronald Chang (Redwood City, CA); Gregory E Mote (Los Angeles, CA); Douglas B Dority (Santa Cruz, CA); Jeffrey S Ross (Lebanon Springs, NY)
Assignee: SYFR, Inc.
G01N1/312G01N35/00029G01N2035/00792
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Quick Facts
Patent No.
US 8,765,453
App. No.
13/330,472
Granted
Jul 1, 2014
Kind
B2
Abstract

Provided is a system and method for staining of one or more samples, including providing one or more self-contained sample processing receptacles, each of the one or more self-contained sample processing receptacles configured to be inserted into an auto-staining instrument; and enabling one of one or more staining procedures appropriate for the one or more samples as a function of a choice of self-contained sample processing receptacle, each of the one or more self-contained sample processing receptacles configured to process each inserted sample of the one or more samples within the self-contained sample processing receptacle.

Claims (12)

1. A system for automatic staining of one or more biological samples, the system comprising:

an auto-staining instrument, wherein the auto-staining instrument is configured to receive one or more sample processing receptacles and comprises fluidic ports and a reader, the reader being configured to obtain an identification of at least one pre-loaded reagent from the one or more sample processing receptacles when the one or more sample processing receptacles are received within the auto-staining instrument;

the one or more sample processing receptacles, wherein each of the one or more sample processing receptacles includes fluid valves, the at least one pre-loaded reagent, and a sealable chamber for sheathing the one or more biological samples to be stained;

reservoirs containing staining procedure fluids coupled to the auto-staining instrument via the fluidic ports of the auto-staining instrument, wherein the fluidic ports are further coupled to the fluidic valves of each of the one or more sample processing receptacles to provide the staining procedure fluids from the reservoirs to the chamber of each of the one or more sample processing reservoirs;

a processor coupled to the auto-staining instrument;

a memory coupled to the processor, the memory encoded with instructions that when executed by the processor comprise the steps of:

accessing a plurality of sample processing procedures;

determining one or more sample processing procedures from the plurality of sample processing procedures appropriate for the one or more sample processing receptacles based on the identification of the at least one pre-loaded reagent from the one or more sample processing receptacles, and

commanding staining of the one or more biological samples within the one or more sample processing receptacles.

2. The system of claim 1 wherein the memory is further encoded with instructions that when executed by the processor comprise the step of comparing identification data from the one or more biological samples with staining procedure data from the one or more sample processing receptacles to confirm that the one or more sample processing receptacles are appropriate for the one or more biological samples.

3. The system of claim 1 wherein the auto-staining instrument is daisy-chained to at least a second auto-staining instrument, the second auto-staining instrument configured to receive at least one of the one or more sample processing receptacles.

4. The system of claim 1 further comprising at least one waste reservoir that receives waste fluids that exit from the one or more sample processing receptacles.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 9, 2012
From: IQBAL, SHAZI; MONTGOMERY, STEVEN M; CHANG, RONALD; MOTE, GREGORY; DORITY, DOUGLAS B; ROSS, JEFFREY S
To: SYFR, INC. (A CALIFORNIA CORPORATION)
Reel/Frame 028349/0922 →
Continuity (2)
Division 12135925 · Jun 9, 2008
Related Publication 20120329140A1 · Dec 27, 2012