IP Library Granted Patent US 8,768,449
Granted Patent B2
US 8,768,449 · App. 12/828,728 · Granted Jul 1, 2014

Prosthetic devices and methods and systems related thereto

Inventors: Bijan Pesaran (Los Angeles, CA); Richard A. Andersen (La Canada, CA)
Assignee: California Institute of Technology
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Quick Facts
Patent No.
US 8,768,449
App. No.
12/828,728
Granted
Jul 1, 2014
Kind
B2
Abstract

Prosthetic devices, methods and systems are disclosed. Eye position and/or neural activity of a primate are recorded and combined. The combination signal is compared with a predetermined signal. The result of the comparison step is used to actuate the prosthetic device.

Claims (32)

1. A prosthetic device able to assume a spatial position on input of a subject, the prosthetic device comprising:

means for recording eye position information of the subject to produce an eye position signal;

means for recording a neural activity of the subject to produce a neural activity signal;

means for storing at least one predetermined behavioral pattern, the at least one predetermined behavioral pattern associated with at least one spatial positioning of the prosthetic device;

processing means coupled to the means for recording eye position information, the means for recording a neural activity and the means for storing, the processing means receiving an eye position signal from the means for recording eye position information during a scan stage occurring after the subject views a plurality of reach goals but before the subject selects one of the plurality of reach goals, receiving a neural activity signal from the means for recording a neural activity signal during neural activity occurring during the scan stage, combining the eye position signal and neural activity signal recorded only during the scan stage to produce a recorded behavioral pattern, predicting a selection of one of a plurality of reach goals by comparing the recorded behavioral pattern and the at least one predetermined behavioral pattern to identify a matching predetermined behavioral pattern, the recorded behavioral pattern associated with a selection of one of the plurality of reach goals after the scan stage, and outputting a spatial position control signal associated with the matching predetermined behavioral pattern; and

means for positioning the prosthetic device coupled to the processing means to receive the spatial position control signal and position the prosthetic device in a spatial position associated with the matching predetermined behavioral pattern.

2. The prosthetic device of claim 1 , wherein the means for recording eye position is configured to record eye position directly.

3. The prosthetic device of claim 1 , wherein the means for recording eye position is configured to record eye position indirectly.

4. The prosthetic device of claim 1 , wherein the means for recording the neural activity is configured to detect spike activity, local field potential (LFP) activity, or both.

5. The prosthetic device of claim 1 , wherein the subject is a primate.

6. A prosthetic device able to assume a spatial position on input of a subject, the prosthetic device comprising:

an eye position recorder to produce an eye position signal;

a neural activity recorder to produce a neural activity signal;

a storage mechanism to store at least one predetermined behavioral pattern, the at least one predetermined behavioral pattern comprising at least one predetermined eye position signal associated with at least one spatial positioning of the prosthetic device;

a processor coupled to the eye position recorder, the neural activity recorder, and the storage mechanism, the processor receiving an eye position signal from the eye position recorder during a scan stage occurring after the subject views a plurality of reach goals but before the subject selects one of the plurality of reach goals, receiving a neural activity signal from the neural activity recorder during neural activity occurring during the scan stage, combining the eye position signal and neural activity signal recorded only during the scan stage to produce a recorded behavioral pattern, predicting a selection of one of a plurality of reach goals by comparing the recorded behavioral pattern and the at least one predetermined behavioral pattern to identify a matching predetermined behavioral pattern, the recorded behavioral pattern associated with a selection of one of the plurality of reach goals after the scan stage and outputting a spatial position control signal associated with the matching predetermined behavioral pattern; and

a control system coupled to the processor to receive the spatial position control signal and to position the prosthetic device in a spatial position associated with the matching predetermined behavioral pattern.

7. The prosthetic device of claim 6 , wherein the eye position recorder is configured to record eye position directly.

8. The prosthetic device of claim 6 , wherein the eye position recorder is configured to record eye position indirectly.

9. The prosthetic device of claim 6 , wherein the neural activity recorder is configured to detect spike activity, local field potential (LFP) activity, or both.

10. The prosthetic device of claim 6 , wherein the subject is a primate.

11. A prosthetic device able to assume a spatial position on input of a subject, the prosthetic device comprising:

means for recording an eye position of the subject to produce an eye position signal;

processing means coupled to the means for recording, the processing means receiving the eye position signal from the means for recording eye position information during a scan stage occurring after the subject views a plurality of reach goals but before the subject selects one of the plurality of reach goals, predicting a selection of one of a plurality of reach goals by comparing a portion of the eye position signal received only during the scan stage with at least one predetermined eye position signal to identify a matching predetermined eye position signal associated with at least one predetermined spatial position of the prosthetic device, the portion of the eye position signal associated with a selection of one of the plurality of reach goals after the scan stage, and outputting a spatial position control signal associated with the predetermined spatial position; and

means for positioning coupled to the processing means to receive the spatial position control signal and position the prosthetic device in a spatial position associated with the matching predetermined eye position signal.

12. The prosthetic device of claim 11 , wherein the means for recording eye position is configured to record eye position indirectly.

13. The prosthetic device of claim 11 , wherein the subject is a primate.

14. A prosthetic device able to assume a spatial position on input of a subject, the prosthetic device comprising:

an eye position recorder to record an eye position of the subject to produce an eye position signal;

a processor coupled to the eye position recorder, the processor receiving the eye position signal from the eye position recorder during a scan stage occurring after the subject views a plurality of reach goals but before the subject selects one of the plurality of reach goals, predicting a selection of one of a plurality of reach goals by comparing a portion of the eye position signal received only during the scan stage with at least one predetermined eye position signal to identify a matching predetermined eye position signal associated with at least one predetermined spatial position of the prosthetic device, the portion of the eye position signal associated with a selection of one of the plurality of reach goals after the scan stage, and outputting a spatial position control signal associated with the predetermined spatial position; and

a control system coupled to the processor to receive the spatial position control signal and to position the prosthetic device in a spatial position associated with the matching predetermined eye position signal.

15. The prosthetic device of claim 14 , wherein the eye position recorder is configured to record eye position indirectly.

16. The prosthetic device of claim 14 , wherein the subject is a primate.

Assignments (3)
CONFIRMATORY LICENSE Recorded Jul 31, 2017
From: CALIFORNIA INSTITUTE OF TECHNOLOGY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 043140/0325 →
CONFIRMATORY LICENSE Recorded Jan 20, 2011
From: CALIFORNIA INSTITUTE OF TECHNOLOGY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 025664/0265 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2010
From: PESARAN, BIJAN; ANDERSEN, RICHARD A.
To: CALIFORNIA INSTITUTE OF TECHNOLOGY
Reel/Frame 024625/0035 →
Continuity (3)
Division 11300965 · Dec 15, 2005
Provisional Application 60636679 · Dec 16, 2004
Related Publication 20100331976A1 · Dec 30, 2010