Sleep monitoring system
View Patent ↗A sleep monitoring system includes an ECG device ( 2 ) and a respiration inductance plethysmogram ( 3 ) which monitor cardiac activity and physical (ribcage) respiration respectively and feed representative signals to a digital data processor. Operations ( 5 - 9 ) process the beat interval data, while in a second thread, operations ( 20 - 24 ) independently process the amplitude modulation of the ECG data caused by the respiratory motion of the subject. The inductance plethysmogram device ( 3 ) provides an input to the processor which represents respiration as directly monitored independently of the ECG. Operations ( 30 - 34 ) process this direct respiration data independently and in parallel, in a third thread. All extracted features are fed to a classifier which in step (10) combines selected combinations of features to make decisions in real time.
1. A sleep monitoring system comprising:
an interface for receiving sensor signals;
wherein the sensor signals include signals from both electrocardiogram and respiration sensors;
a processor for extracting a plurality of features from the sensor signals; and
the processor is configured to operate as a classifier for generating an output indicating a sleep stage based upon classification of the plurality of extracted features, wherein at least one of the plurality of extracted features includes a measure of respiration and electrocardiogram derived respiratory (EDR) features, and
wherein the classifier uses a combination of the plurality of extracted features derived from frequency-domain and time-domain parameters of the electrocardiogram and respiration sensor signals to provide an estimate of the sleep stage based on probability distributions of the extracted features.
2. A sleep monitoring system as claimed in claim 1 , wherein the processor extracts time domain and frequency domain features from the measure of respiration.
3. A sleep monitoring system as claimed in claim 1 or 2 , wherein the processor measures heartbeat intervals from cardiogram sensor signals and uses said measurements to extract features.
4. A sleep monitoring system as claimed in claim 3 , wherein the extracted features include mean interval per epoch, standard deviation of intervals, longest interval, and shortest interval.
5. A sleep monitoring system as claimed in claim 3 , wherein the processor measures amplitude modulation of the cardiogram sensor signals caused by respiratory motion of a person and uses said measurement to extract features.
6. A sleep monitoring system as claimed in claim 5 , wherein the extracted features include variance of a derived respiratory signal, and power of the respiratory signal at a frequency band.
7. A sleep monitoring system as claimed in claim 5 , wherein the extracted features include the dominant frequency of respiration and the power at the dominant respiratory frequency.
8. A sleep monitoring system as claimed in claim 5 , wherein the processor independently extracts features from the heartbeat interval measurements and from the amplitude modulation measurements.
9. A sleep monitoring system as claimed in claim 1 , wherein the interface receives sensor signals from a device for physically monitoring patient respiration.
10. A sleep monitoring system as claimed in claim 9 , wherein the processor measures variations in signals from said device.
11. A sleep monitoring system as claimed in claim 9 or 10 , wherein the processor uses said measurements to independently extract features.
12. A sleep monitoring system as claimed in claim 9 or 10 , wherein the features extracted by the processor from the signals from said device include ribcage respiration effort in each of a plurality of frequency bands, envelope power, and breath length variation.
13. A sleep monitoring system as claimed in claim 1 , wherein the interface receives sensor signals from devices simultaneously monitoring patient respiration and patient cardiograms, and the processor simultaneously processes said signals.
14. A sleep monitoring system as claimed in claim 13 , wherein said device comprises an inductance plethysmograph.
15. A sleep monitoring system as claimed in claim 9 , wherein the processor uses measurements from said sensor signals to extract a first set of features and independently uses sensor signals derived from a cardiogram to extract a second set of features.
16. A sleep monitoring system as claimed in claim 1 , wherein the features are extracted for each of a series of epochs.
17. A sleep monitoring system as claimed in claim 16 , wherein the epochs have a duration of less than 30 seconds.
18. A sleep monitoring system as claimed in claim 16 , wherein the processor extracts a plurality of detrended features derived from a plurality of epochs in a sequence.
19. A sleep monitoring system as claimed in claim 18 , wherein the detrended features are generated by subtracting a local mean signal from epoch feature values.
20. A sleep monitoring system as claimed in claim 1 , wherein the classifier operates according to a discriminant classifier model.
21. A sleep monitoring system as claimed in claim 1 , wherein the search process identifies an optimal subset of features to use for classification performance.
22. A sleep monitoring system as claimed in claim 21 , wherein the sequential forward floating search process uses a coefficient that is a measure of an inter-rater agreement taking account of a prior probability of a specific class occurring.
23. A sleep monitoring system as claimed in claim 22 , wherein said process executes passes which add a feature that most improves performance to already-selected features.
24. A sleep monitoring system as claimed in claim 1 , wherein the classifier generates the output indicating sleep stage based upon a subset of the plurality of extracted features.