Apoaequorin-containing compositions and methods of using same
Compositions containing apoaequorin and methods for their use in treating symptoms and disorders related to calcium imbalances associated with, for example, sleep quality, energy quality, mood quality, memory quality or pain are provided by the present invention.
1. A method for treating a symptom or disorder associated with calcium imbalance, comprising administering to a subject in need of such treatment an effective amount of apoaequorin, wherein said apoaequorin is not administered with its cofactor, coelenterazine.
2. The method according to claim 1 , wherein the symptom or disorder associated with calcium imbalance is sleep-related and administration of apoaequorin to said subject improves sleep quality in the subject.
3. The method according to claim 1 , wherein the symptom or disorder associated with calcium imbalance is energy-related and administration of apoaequorin to said subject improves energy quality in the subject.
4. The method according to claim 1 , wherein the symptom or disorder associated with calcium imbalance is mood-related and administration of apoaequorin to said subject improves mood quality in the subject.
5. The method according to claim 1 , wherein the symptom or disorder associated with calcium imbalance is pain-related and administration of apoaequorin to said subject alleviates pain in the subject.
6. The method according to claim 1 , wherein the symptom or disorder associated with calcium imbalance is memory-related and administration of apoaequorin to said subject improves memory, as indicated by improved scores on a standardized cognitive assessment.
7. The method according to claim 1 , wherein the symptom or disorder associated with calcium imbalance is related to neuronal excitability, muscle contraction, membrane permeability, cell division, hormone secretion, bone mineralization, or cell death following ischemia.
8. The method according to claim 1 , wherein apoaequorin is administered to said subject in the form of a nutraceutical composition.
9. The method according to claim 1 , wherein apoaequorin is administered to said subject in the form of a capsule for oral delivery.