Granted Patent
B2
US 8,816,088 · App. 13/964,484 · Granted Aug 26, 2014
Diamide compounds having muscarinic receptor antagonist and β
Inventors:
Adam D. Hughes (Belmont, CA); Yan Chen (Foster City, CA); John R. Jacobsen (San Mateo, CA); Eric L. Stangeland (Pacifica, CA); Rose Yen (San Francisco, CA)
Assignee:
Theravance Respiratory Company, LLC
View Patent ↗
Loading inventors, assignments & file history…
Abstract
This invention relates to a compound of formula I: or a pharmaceutically acceptable salt thereof. Such compounds possess both muscarinic receptor antagonist and β 2 adrenergic receptor agonist activities. The invention also relates to pharmaceutical compositions comprising such compounds, processes and intermediates for preparing such compounds, and methods of using such compounds as bronchodilating agents to treat pulmonary disorders.
Claims (1)
1. Biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}phenylcarbamoyl)-butyl]methylcarbamoyl}ethyl)piperidin-4-yl ester of the formula:
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 12, 2020
From: THERAVANCE RESPIRATORY COMPANY, LLC
To: THERAVANCE BIOPHARMA R&D IP, LLC
Reel/Frame 054393/0695 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 10, 2014
From: THERAVANCE, INC.
To: THERAVANCE RESPIRATORY COMPANY, LLC
Reel/Frame 033175/0547 →
Continuity (4)
Provisional Application
61172039
· Apr 23, 2009