IP Library Granted Patent US 8,821,566
Granted Patent B2
US 8,821,566 · App. 13/138,245 · Granted Sep 2, 2014

Alloy for medical use and medical device

Inventors: Kenichi Hamada (Tokushima, JP); Eiichi Honda (Tokushima, JP); Kenzo Asaoka (Tokushima, JP); Midori Yoshida (Tokushima, JP)
Assignee: The University of Tokushima
A61L31/022C22F1/14A61L31/18A61N1/375G01R33/288A61F2/82C22C5/02A61N2001/086
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Quick Facts
Patent No.
US 8,821,566
App. No.
13/138,245
Granted
Sep 2, 2014
Kind
B2
Abstract

Provided is alloy for medical use and a medical device that is novel and useful. The alloy for medical use according to, for example, an embodiment of the present invention is mainly composed of three kinds of elements of gold (Au), platinum (Pt), and niobium (Nb). A total content of the three kinds of elements can be no smaller than 99% by weight, in which a platinum content can be no smaller than 5% by weight and no greater than 50% by weight and a niobium content can be no smaller than 3% by weight and no greater than 15% by weight. By adjusting the content ratio of the three elements, for example, it is possible to reduce or prevent artifacts in an MRI. Non-magnetization is also possible.

Claims (39)

1. Alloy for medical use consisting essentially of:

three kinds of elements of gold (Au), platinum (Pt), and niobium (Nb).

2. The alloy for medical use according to claim 1 , wherein

artifacts in MRI are reduced.

3. The alloy for medical use according to claim 1 , wherein

a total content of the three kinds of elements is no smaller than 99% by weight.

4. The alloy for medical use according to claim 1 , wherein

an element different from the three kinds of elements is added in a range that allows reduction of artifacts.

5. The alloy for medical use according to claim 4 , wherein

a total content of the three kinds of elements is no smaller than 98% by weight.

6. The alloy for medical use according to claim 1 , wherein

a total content of the three kinds of elements is no smaller than 95% by weight.

7. The alloy for medical use according to claim 1 , wherein

a platinum content is no smaller than 5% by weight and no greater than 27% by weight, and niobium content is no smaller than 3% by weight and no greater than 15% by weight.

8. The alloy for medical use according to claim 1 , wherein

a platinum content is no smaller than 5% by weight and no greater than 25% by weight, and niobium content is no smaller than 7% by weight and no greater than 12% by weight.

9. The alloy for medical use according to claim 1 , wherein,

within a compositional representation of the alloy on a Cartesian coordinate system with an x-axis is a platinum content (% by weight) and a y-axis is a niobium content (% by weight), the compositional representation includes an area enclosed by the following (X, Y) values: (5, 8), (10, 8), (15, 10), (20, 9), (25, 7), (25, 9), (20, 11), (15, 12), and (5, 8).

10. The alloy for medical use according to claim 1 , wherein,

within a compositional representation of the alloy on a Cartesian coordinate system with an x-axis is a platinum content (% by weight) and a y-axis is a niobium content (% by weight), the compositional representation includes an area enclosed by the following (X, Y) values:

(25, 9), (25, 7), (50, 9), and (50, 7).

11. The alloy for medical use according to claim 1 , wherein

the alloy is not magnetically susceptible.

12. The alloy for medical use according to claim 1 , wherein

a platinum content of the alloy is no smaller than 5% by weight and no greater than 50% by weight, and a niobium content is no smaller than 7% by weight and no greater than 11% by weight.

13. The alloy for medical use according to claim 1 , wherein

an absolute value of magnetic susceptibility of the alloy is no greater than 24 ppm.

14. The alloy for medical use according to claim 1 , wherein

an absolute value of a difference from an absolute value of magnetic susceptibility of the alloy and a magnetic susceptibility of water (9 ppm) is no greater than 15 ppm.

15. The alloy for medical use according to claim 1 , wherein

Vickers hardness is no smaller than 180.

16. The alloy for medical use according to claim 15 , wherein

Vickers hardness is set to be no smaller than 180 by melting and coagulating the three elements and carrying out an aging heat treatment to the three elements.

17. A medical device, comprising:

the alloy for medical use according to claim 1 .

18. The medical device according to claim 17 , wherein

the medical device is one selected from (1) a stent, a coil, or a clip including an aneurysm clip, (2) a housing of an implantable artificial heart, (3) a casing, an electrode, or a terminal of a cardiac pacemaker, (4) an artificial valve frame, and (5) a surgical implement used under an MRI environment.

19. The medical device according to claim 17 , wherein

the medical device is used in angiography according to a gradient echo method.

Assignments (2)
CHANGE OF NAME Recorded Jan 27, 2017
From: THE UNIVERSITY OF TOKUSHIMA
To: TOKUSHIMA UNIVERSITY
Reel/Frame 041519/0395 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 6, 2011
From: HAMADA, KENICHI; HONDA, EIICHI; ASAOKA, KENZO; YOSHIDA, MIDORI
To: TOKUSHIMA, THE UNIVERSITY OF
Reel/Frame 027188/0117 →
Priority Claims (1)
JP 2009-013725 · Jan 24, 2009 · national
Continuity (1)
Related Publication 20120035632A1 · Feb 9, 2012