Portable rapid diagnostic test reader
A portable rapid diagnostic test reader system includes a mobile phone having a camera and one or more processors contained within the mobile phone and a modular housing configured to mount to the mobile phone. The modular housing including a receptacle configured to receive a sample tray holding a rapid diagnostic test. At least one illumination source is disposed in the modular housing and located on one side of the rapid diagnostic test. An optical demagnifier is disposed in the modular housing interposed between the rapid diagnostic test and the mobile phone camera.
1. A portable rapid diagnostic test reader system comprising:
a mobile phone having a camera and one or more processors contained within the mobile phone, the mobile phone containing imaging software thereon executable by the one or more processors;
a modular housing configured to mount to the mobile phone, the modular housing including a receptacle configured to receive a rapid diagnostic test or a sample tray holding a rapid diagnostic test, the rapid diagnostic test comprising a test location and a control location;
at least one illumination source disposed in the modular housing and located on one side of the rapid diagnostic test;
an optical demagnifier disposed in the modular housing, the optical demagnifier demagnifying the image of the rapid diagnostic test to place the test location and control location in a field of view of the mobile phone camera; and
wherein the imaging software extracts regions of interest from the test location and the control location in an image of the field of view and compares respective regions of interest with respective threshold values and characterizes the rapid diagnostic test.
2. The portable rapid diagnostic test reader system of claim 1 , wherein the optical demagnifier comprises free space, a lens or multiple lenses.
3. The portable rapid diagnostic test reader system of claim 1 , wherein the at least one illumination source transmits illumination through the rapid diagnostic test and onto the camera of the mobile phone.
4. The portable rapid diagnostic test reader system of claim 1 , wherein the at least one illumination source reflects illumination off the rapid diagnostic test and onto the mobile phone camera.
5. The portable rapid diagnostic test reader system of claim 1 , wherein the at least one illumination source comprises an array of individual illumination sources.
6. The portable rapid diagnostic test reader system of claim 1 , wherein the rapid diagnostic test comprises a fluorescent test, and the at least one illumination source emits illumination at a wavelength that causes the rapid diagnostic test to fluoresce.
7. The portable rapid diagnostic test reader system of claim 1 , further comprising a removable color filter interposed between the camera of the mobile phone and the rapid diagnostic test.
8. The portable rapid diagnostic test reader system of claim 1 further comprising:
a second illumination source disposed in the modular housing and located at a second, opposing side of the rapid diagnostic test; and
a switch to selectively illuminate the rapid diagnostic test with either the first illumination source or the second illumination source.
9. The portable rapid diagnostic test reader system of claim 1 , further comprising a plurality of sample trays, wherein each of the plurality of sample trays is configured to a particular rapid diagnostic test.
10. The portable rapid diagnostic test reader system of claim 1 , wherein the first illumination source comprises an array of individual illumination sources disposed on a side of the rapid diagnostic test opposite the mobile phone.
11. The portable rapid diagnostic test reader system of claim 8 , wherein the second illumination source comprises first and second arrays of individual illumination sources disposed on a side of the rapid diagnostic test nearest the mobile phone, the first and second arrays of individual illumination sources configured to reflect illumination from the rapid diagnostic test and onto the mobile phone camera.
12. The portable rapid diagnostic test reader system of claim 1 , further comprising a power source disposed in the housing.
13. The portable rapid diagnostic test reader system of claim 8 , wherein the first and second illumination sources are powered by a power source of the mobile phone.
14. The portable rapid diagnostic test reader system of claim 8 , wherein the switch is connected to an audio jack of the mobile phone.
15. The portable rapid diagnostic test reader system of claim 8 , further comprising a visual indicator configured to indicate proper loading of the sample tray holding a rapid diagnostic test within the housing.
16. The portable rapid diagnostic test reader system of claim 1 , wherein the at least one light source emits illumination at a wavelength range that causes the rapid diagnostic test to fluoresce.
17. The portable rapid diagnostic test reader system of claim 1 , wherein the sample tray comprises a sample tray configured to hold multiple different types of rapid diagnostic tests.
18. The portable rapid diagnostic test reader system of claim 1 , wherein the rapid diagnostic test comprises one of a strip, dipstick, cassette, card, and pad.
19. The portable rapid diagnostic test reader system of claim 8 , wherein at least one of the first illumination source and the second illumination source comprises a tunable wavelength.
20. A portable rapid diagnostic test reader system comprising:
a mobile phone having a camera and one or more processors contained within the mobile phone, the mobile phone containing imaging software thereon executable by the one or more processors;
a modular housing configured to mount to the mobile phone, the modular housing including a receptacle configured to receive a rapid diagnostic test, the rapid diagnostic test comprising a test location and a control location;
a first illumination source disposed in the modular housing and configured to transmit illumination through the rapid diagnostic test and onto the camera in a transmission mode;
a second illumination source disposed in the modular housing and configured to reflect illumination off the rapid diagnostic test and onto the camera in a reflection mode
a switch for actuating the first illumination source and the second illumination source; and
wherein the imaging software extracts regions of interest from the test location and the control location in an image of the field of view and compares respective regions of interest with respective threshold values and characterizes the rapid diagnostic test.
21. The portable rapid diagnostic test reader system of claim 20 , wherein the characterization of the rapid diagnostic test reader comprises data corresponding to the quantification of a response, detection, or sensing level.
22. The portable rapid diagnostic test reader system of claim 20 , wherein the characterization of the rapid diagnostic test reader comprises data corresponding to a positive/negative evaluation.
23. The portable rapid diagnostic test reader system of claim 1 , wherein the characterization of the rapid diagnostic test reader comprises data corresponding to the quantification of a response, detection, or sensing level.
24. The portable rapid diagnostic test reader system of claim 1 , wherein the characterization of the rapid diagnostic test reader comprises data corresponding to a positive/negative evaluation.