Agmatine containing dietary supplements, nutraceuticals, and foods
View Patent ↗The invention is dietary supplements, nutraceutical compositions, medical foods, and animal feeds that have cytoprotective (cell and tissue protection) and health promoting effects. The compositions contain a high dose range of agmatine and nutraceutical acceptable salts thereof as dietary fortification for providing effective long-term cytoprotection and affording for soft stool. The compositions may contain agmatine alone or in combination with other dietary ingredients having health promoting effects. The compositions can be prepared with dietary accepted excipients and compatible forms of carriers, including but not limited to, powders, tablets, capsules, controlled release carriers, lozenges and chewable preparations, liquid suspensions, suspensions in an edible supporting matrix or foodstuff and oral rehydration solutions, to enable consumption of said compositions.
1. A method of promoting the recovery of neurotraumatized cells by prophylactically treating healthy cells, the method comprising the following agmatine regimen:
administering a dietary supplement that includes an agmatine salt to a human who is asymptomatic for any neuropathy or neurological disorders, comprising
an amount of the agmatine salt in a megadose range of 1780 milligrams per 70 kilograms body weight per day to 3560 milligrams per 60 kilograms body weight per day;
continuing the administration of said dietary supplement on a daily basis, but for at least 21 days;
discontinuing the administration of said dietary supplement when said human experiences a neurological trauma after said at least 21 days of administration of said dietary supplement; and,
wherein said neurotraumatized cells correspond to said healthy cells after said healthy cells experience a neurotraumatic event;
whereby said agmatine regimen promotes recovery of neurotraumatized cells more quickly than said neurotraumatized cells would otherwise be able to do.
2. The method of claim 1 , wherein the dietary supplement further comprises
one or more dietary ingredients selected from the group consisting of minerals, fatty acids, metabolites, amino acids, phytonutrients, vitamins, and coenzymes.
3. The method of claim 2 , wherein the dietary supplement further comprises
an excipient
wherein said excipient enables consumption of said dietary supplement.
4. The method of claim 1 , wherein the dietary supplement further comprises
an excipient
wherein said excipient enables consumption of said dietary supplement.
5. The method of claim 1 , wherein the dietary supplement further comprises
a medical food portion;
wherein said dietary supplement is incorporated into said medical food portion.
6. The method of claim 5 , wherein the dietary supplement further comprises
one or more dietary ingredients selected from the group consisting of minerals, fatty acids, metabolites, amino acids, phytonutrients, vitamins, and coenzymes.
7. The method of claim 1 further comprising
providing a processed food comprising
the dietary supplement and
a food portion;
wherein said dietary supplement is incorporated into said food portion.
8. The method of claim 7 , wherein said food portion is fortified with one or more health promoting ingredients.
9. The method of claim 8 , wherein said food portion is selected from the group consisting of cereals and fermented dairy products.
10. The method of claim 1 further comprising
providing a processed beverage comprising
the dietary supplement and
a beverage portion;
wherein said dietary supplement is incorporated into said beverage portion.
11. The method of claim 10 , wherein said beverage portion is fortified with one or more health promoting ingredients.
12. The method of claim 11 , wherein said beverage portion is selected from the group consisting of tea, juice, water, and alcoholic beverages.
13. The method of claim 1 , wherein the promoting of the recovery of neurotraumatized cells is further characterized by promoting accelerated nerve regeneration.
14. A method of promoting the recovery of neurotraumatized cells by prophylactically treating healthy cells, the method comprising the following agmatine regimen:
administering a dietary supplement that includes an agmatine salt to an animal that is asymptomatic for any neuropathy or neurological disorders, comprising
an amount of the agmatine salt in a megadose range of 10 milligrams per kilograms body weight per day to 500 milligrams per kilograms body weight per day;
continuing the administration of said dietary supplement on a daily basis, but for a at least 21 days; and,
discontinuing the administration of said dietary supplement when said animal experiences a neurological trauma after said at least 21 days of administration of said dietary supplement;
wherein said neurotraumatized cells correspond to said healthy cells after said healthy cells experience a neurotraumatic event;
whereby said agmatine regimen promotes recovery of neurotraumatized cells more quickly than said cells would otherwise be able to do.
15. The method of claim 14 , wherein said animals are selected from a group consisting of rats and mice, and wherein said effective dose range amount of agmatine for said rats and mice comprises 200 milligrams per kilogram body weight per day to 500 milligrams per kilogram body weight per day of the agmatine salt.
16. The method of claim 14 , wherein said animals are dogs, and wherein said effective dose range amount of agmatine for said dogs comprises 20 milligrams per kilogram body weight per day to 80 milligrams per kilogram body weight per day of the agmatine salt.
17. The method of claim 14 , wherein said animals are horses, and wherein said effective dose range amount of agmatine for said horses comprises 10 milligrams per kilogram body weight per day to 40 milligrams per kilogram body weight per day of the agmatine salt.
18. The method of claim 14 further comprising
providing a processed food comprising
the dietary supplement and
an animal feed,
wherein said dietary supplement is incorporated into said animal feed.
19. The method of claim 14 , wherein the promoting of the recovery of neurotraumatized cells is further characterized by promoting accelerated nerve regeneration.