IP Library › Granted Patent US 8,932,623
Granted Patent B2
US 8,932,623 · App. 13/217,852 · Granted Jan 13, 2015

Protective wound dressing device for oral and pharyngeal space

Inventor: Scott Alan Keplinger (Durham, NC)
Assignee: Ethicon, Inc.
A61L26/0052A61F13/122A61L15/24A61L15/32A61L15/58A61L15/62A61L15/64A61L24/06A61L26/0014A61L26/0038A61L2430/36
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Quick Facts
Patent No.
US 8,932,623
App. No.
13/217,852
Granted
Jan 13, 2015
Kind
B2
Abstract

The present invention provides a wound dressing comprising a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof and a 1,1-disubstituted ethylene monomer. The present invention further provides methods of using the wound dressing and kits containing the wound dressing.

Claims (23)

1. A wound dressing comprising:

A) a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof; and

B) a 1,1-disubstituted ethylene monomer.

2. The wound dressing of claim 1 wherein said 1,1-disubstituted ethylene monomer comprises a cyanoacrylate.

3. The wound dressing of claim 2 wherein said cyanoacrylate is selected from the group consisting of ethyl cyanoacrylate, n-butyl cyanoacrylate, 2-octyl cyanoacrylate, methoxyethyl cyanoacrylate, ethoxyethyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, 1-methoxy-2-propyl cyanoacrylate, hexyl cyanoacrylate, butyl lactoyl cyanoacrylate, butyl glycolcyl cyanoacrylate, ethyl lactoyl cyanoacrylate, and ethyl glycoloyl cyanoacrylate.

4. The wound dressing of claim 1 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 5 mm in any given dimension.

5. The wound dressing of claim 1 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 3 mm in any given dimension.

6. A method of treating a wound comprising:

(1) (a) applying a 1,1-disubstituted monomer to a wound and embedding a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof in said 1,1-disubstituted ethylene monomer, or

(b) applying a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof to a wound and applying a 1,1-disubstituted monomer to the wound filling at least a portion of at least one cell of the water-soluble molding matrix;

(2) polymerizing the 1,1-disubstituted ethylene monomer; and

(3) dissolving said water-soluble molding matrix leaving a molded polymer applied to said wound.

7. The method of claim 6 wherein said 1,1-disubstituted ethylene monomer comprises a cyanoacrylate.

8. The method of claim 7 wherein said cyanoacrylate is selected from the group consisting of ethyl cyanoacrylate, n-butyl cyanoacrylate, 2-octyl cyanoacrylate, methoxyethyl cyanoacrylate, ethoxyethyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, 1-methoxy-2-propyl cyanoacrylate, hexyl cyanoacrylate, butyl lactoyl cyanoacrylate, butyl glycolcyl cyanoacrylate, ethyl lactoyl cyanoacrylate, and ethyl glycoloyl cyanoacrylate.

9. The method of claim 6 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 5 mm in any given dimension.

10. The wound dressing of claim 6 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 3 mm in any given dimension.

11. A kit comprising:

A) at least one tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof; and

B) at least one 1,1-disubstituted ethylene monomer.

12. The kit of claim 11 wherein said 1,1-disubstituted ethylene monomer comprises a cyanoacrylate.

13. The kit of claim 12 wherein said cyanoacrylate is selected from the group consisting of ethyl cyanoacrylate, n-butyl cyanoacrylate, 2-octyl cyanoacrylate, methoxyethyl cyanoacrylate, ethoxyethyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, 1-methoxy-2-propyl cyanoacrylate, hexyl cyanoacrylate, butyl lactoyl cyanoacrylate, butyl glycolcyl cyanoacrylate, ethyl lactoyl cyanoacrylate, and ethyl glycoloyl cyanoacrylate.

14. The kit of claim 11 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 5 mm in any given dimension.

15. The kit of claim 11 wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 3 mm in any given dimension.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 25, 2011
From: KEPLINGER, SCOTT ALAN
To: ETHICON, INC.
Reel/Frame 026808/0923 →
Continuity (1)
Related Publication 20130052152A1 · Feb 28, 2013