Devices for approximating tissue and related methods of use
Devices for approximating multiple tissue edges internal to a body are disclosed.
1. A device to approximate multiple tissue edges, removably connected to a distal end of an elongate member having a handle disposed at a proximal end of the elongate member opposite the distal end of the elongate member, the device comprising:
a fixed element having a proximal end and a distal end, the proximal end of the fixed element disposed closer to the proximal end of the elongate member than the distal end of the fixed element;
a plurality of jaws each having a first end and a second end, the plurality of jaws being coupled at respective first ends to the fixed element; and
an actuating member coupled to each of the plurality of jaws,
wherein:
the respective first ends of each of the plurality of jaws are disposed closer to the proximal end of the fixed element than the second ends, and wherein each jaw is configured to move with respect to the fixed element from an open configuration to a closed configuration, the open configuration being a configuration wherein the second end of the respective jaw is located away from the fixed element and the closed configuration being a configuration wherein the second end of the respective jaw mates with the fixed element to grasp one or more tissue edges between the respective jaw and the fixed element;
the respective first ends of each of the plurality of jaws are coupled to the fixed element at longitudinally staggered positions;
each of the plurality of jaws is moved from the open configuration to the closed configuration via proximal movement of the actuating member; and
a first jaw of the plurality of jaws bends radially outward from a first flex point, and a second jaw of the plurality of jaws bends radially outward from a second flex point proximal to the first flex point.
2. The device of claim 1 , wherein the fixed element includes barbs, the barbs being configured to pierce the one or more tissue edges between at least one of the plurality of jaws and the fixed element.
3. The device of claim 1 , wherein the fixed element includes teeth configured to grasp a tissue edge between the jaw and the fixed element.
4. The device of claim 1 , wherein each of the plurality of jaws includes teeth configured to grasp a tissue edge between the jaw and the fixed element.
5. The device of claim 1 , wherein each of the plurality of jaws is configured to move independently relative to the fixed element.
6. The device of claim 1 , wherein the plurality of jaws are configured to move together relative to the fixed element.
7. The device of claim 1 , wherein the device is releasable from the elongate member via a frangible or electrolysis link.
8. The device of claim 1 , wherein the device is releasably connected to the elongate member via mating threads.
9. The device of claim 1 , wherein the fixed element and each of the plurality of jaws includes teeth configured to grasp tissue edges between the fixed element and the jaws.
10. The device of claim 9 , wherein the teeth on the plurality of jaws lock with the teeth on the fixed element to keep the jaws in the closed configuration.
11. The device of claim 1 , further including an end cap proximal to the fixed element, the fixed element and the plurality of jaws configured to slide proximally into the end cap via the proximal movement of the actuating member.
12. The device of claim 11 , wherein:
the proximal movement of the actuating member to a first intermediate position causes the second jaw of the plurality of jaws to contact the end cap and move from the open configuration to the closed configuration; and
the proximal movement of the actuating member from the first intermediate position to a second intermediate position causes the first jaw of the plurality of jaws to contact the end cap and move from the open configuration to the closed configuration.
13. A device to approximate multiple tissue edges, comprising:
a fixed element; and
a first jaw and a second jaw each having a first end and a second end, the first end of the first jaw being coupled to the fixed element at a first position, the first end of the second jaw being coupled to the fixed element at a second position, wherein:
each jaw is configured to move with respect to the fixed element from an open configuration to a closed configuration, the open configuration being a configuration wherein the second end of the respective jaw is located away from the fixed element and the closed configuration being a configuration wherein the second end of the respective jaw mates with the fixed element to grasp one or more tissue edges between the respective jaw and the fixed element;
the first and second positions are longitudinally staggered from one another; and
the first jaw bends radially outward from a first flex point, and the second jaw bends radially outward from a second flex point proximal to the first flex point.
14. The device of claim 13 , further including an end cap proximal to the fixed element, the fixed element and the first and second jaws being configured to slide proximally into the end cap.
15. A device to approximate multiple tissue edges, comprising:
a fixed element;
a plurality of jaws each having a first end and a second end, the plurality of jaws being coupled at respective first ends to the fixed element; and
an actuating member coupled to each of the plurality of jaws, wherein:
each jaw is configured to move with respect to the fixed element from an open configuration to a closed configuration, the open configuration being a configuration wherein the second end of the respective jaw is located away from the fixed element and the closed configuration being a configuration wherein the second end of the respective jaw mates with the fixed element to grasp one or more tissue edges between the respective jaw and the fixed element;
the respective first ends of each of the plurality of jaws are coupled to the fixed element at longitudinally staggered positions;
each of the plurality of jaws is moved from the open configuration to the closed configuration via proximal movement of the actuating member; and
a first jaw of the plurality of jaws bends radially outward from a first flex point, and a second jaw of the plurality of jaws bends radially outward from a second flex point proximal to the first flex point.
16. The device of claim 15 , wherein the proximal movement of the actuating member to a first intermediate position causes the second jaw of the plurality of jaws to move from the open configuration to the closed configuration, while the first jaw of the plurality of jaws remains in the open configuration.
17. The device of claim 16 , wherein the proximal movement of the actuating member from the first intermediate position to a second intermediate position causes the first jaw of the plurality of jaws to move from the open configuration to the closed configuration.