Concentrate of omega 3
An efficient and simple process to obtain a concentrate that includes over 80% in weight of ethyl esters of ω-3 fatty acids based on a composition of matter that contains esters of ω-3 fatty acids or free ω-3 fatty acids that comprises the stages of: a) contacting the composition of matter with ethanol of at least 96% in weight and a hydroxide of an alkali metal at a temperature between 60 and 200° C. to form a liquid mixture that includes alkaline salts of fatty acids; b) cool the liquid mixture to a temperature between 50 and −20° C. to form a solid phase and a liquid phase and separate the liquid phase from the solid phase; c) contact the separated liquid phase of stage b) with an acid to form an acidified mixture with a water content under 10%, where the mixture consists of a solid phase that includes the alkali metal salt of the acid and a liquid phase that comprises ω-3 fatty acids; d) heat the mixture of stage c) between 50 to 150° C. in the presence of an esterification catalyst to form a mixture that includes ethyl esters of ω-3 fatty acids; e) contact the mixture of stage d) with an alkali to form a neutralized mixture; f) distill the neutralized mixture to obtain a distillate that includes over 80% in weight of ethyl esters of ω-3 fatty acids.
1. A process for obtaining a concentrate containing more than 80% by weight of ethyl esters of ω-3 fatty acids based on a composition of matter that contains esters of ω-3 fatty acids or free ω-3 fatty acids, which comprises:
a) contacting the composition of matter with ethanol of at least 96% in weight and a hydroxide of an alkaline metal at a temperature between 60 and 200° C. to form a liquid mixture that includes alkaline salts of fatty acids;
b) cooling the liquid mixture to a temperature between 50 and −20° C. to form a solid phase and a liquid phase and separating the liquid phase from the solid phase;
c) contacting the separated liquid phase of stage b) with an acid to form an acidified mixture with a water content under 10%, wherein the mixture consists of a solid phase that includes the alkali metal salt of the acid and a liquid phase that comprises ω-3 fatty acids;
d) heating the mixture of stage c) to between 50 and 150° C. in the presence of an esterification catalyst to form a mixture that includes ethyl esters of ω-3 fatty acids;
e) contacting the mixture of stage d) with an alkali to form a neutralized mixture; and
f) distilling the neutralized mixture to obtain a distillate that contains in excess of 80% by weight of ethyl esters of ω-3 fatty acids.
2. The process according to claim 1 , wherein the temperature in stage a) is between 90 to 150° C.
3. The process according to claim 2 , wherein the temperature in stage a) is 120° C.
4. The process according to claim 1 , wherein the temperature in stage b) is between 50 and 0° C.
5. The process according to claim 1 , wherein the acid in stage c) is a member selected from the group consisting of sulfuric acid and hydrochloric acid.
6. A concentrate of ethyl esters of ω-3 fatty acids that contains more than 80% by weight of ethyl esters of ω-3 fatty acids produced according to claim 1 , wherein the ω-3 fatty acids of the ethyl esters have the all cis configuration and all their double bonds are separated one from another by a methylene unit.