Peptide having antibacterial or anti-inflammatory activity and pharmaceutical composition containing the same as an active ingredient
A peptide having antibacterial or anti-inflammatory activity and a pharmaceutical composition containing the same as an active ingredient are described. Also, a peptide having antibacterial or anti-inflammatory activity against dental bacteria, including periodontal pathogens, and bacteria causing atopic dermatitis, and a pharmaceutical composition containing the peptide as an active ingredient are described. The inventive peptide having antibacterial or anti-inflammatory activity can be used for the treatment of both dental infectious diseases, including periodontitis, and inflammations, including arthritis.
1. An antibacterial composition containing the isolated peptide consisting of an amino acid sequence of SEQ ID NO: 2 as an active ingredient.
2. A composition for treating dental infectious disease containing the isolated peptide consisting of an amino acid sequence of SEQ ID NO: 2 as an active ingredient.
3. The composition of claim 2 , wherein the dental infectious disease is selected from the group consisting of gingivitis, periodontitis, and peri-implantitis.
4. The composition of claim 2 , wherein the composition is formulated in the form of a gel.
5. The composition of claim 2 , further comprising a pharmaceutically acceptable carrier.
6. The composition of claim 5 , wherein the composition is formulated in the form of a gel.
7. The composition of claim 1 , wherein the composition contains the peptide in an amount of 10 −3 to 1 part by weight.
8. The composition of claim 2 , wherein the composition contains the peptide in an amount of 10 −3 to 1 part by weight.