Method of manufacturing a nicotine delivery product

1. A method for preparing a nicotine delivery product; said method comprising:

(a) mixing an aqueous suspension of a nicotine/cation exchange resin complex with glycerol or an aqueous solution or suspension thereof forming a mixture comprising a paste, wherein the total amount of water is from 26 to 45% by weight of the total mixture; wherein the resin is polacrilex; and

(b) removing water from the paste to produce said nicotine delivery product having a release rate of 80% or more over a 10 minute time period.

2. The method as claimed in claim 1 wherein the total amount of water present in the paste is from 30 to 40% by weight of the total mixture.

3. The method as claimed in claim 2 wherein the total amount of water present in the paste is about 35% by weight of the total mixture.

4. A method for preparing a nicotine delivery product; said method comprising

(a) mixing an aqueous solution of nicotine with a cation exchange resin forming a nicotine/cation exchange resin complex;

(b) admixing to said complex of step (a) an aqueous solution or suspension of glycerol to form a mixture comprising a paste, wherein the nicotine/cation exchange resin complex incorporates the glycerol and the total amount of water is from 26 to 45% by weight of the total mixture; wherein the resin is polacrilex; and

(c) removing water from said paste to produce said nicotine delivery product having a release rate of 80% or more over a 10 minute time period.

5. The method according to claim 4 , wherein the concentration of nicotine in said aqueous solution of nicotine is from about 5% by weight to about 50% by weight.

6. The method according to claim 1 , wherein the ratio of cation exchange resin to nicotine is from 1:1 to 10:1.

7. The method according to claim 6 , wherein the ratio of cation exchange resin to nicotine is from 2:1 to 6:1.

8. The method according to claim 6 , wherein the ratio of cation exchange resin to nicotine is about 4:1.

9. The method according to claim 1 , wherein the ratio of cation exchange resin to glycerol is from 1:1 to 10:1.

10. The method according to claim 9 , wherein the ratio of cation exchange resin to glycerol is from 2:1 to 8:1.

11. The method according to claim 9 , wherein the ratio of cation exchange resin to glycerol is about 2.4:1.

12. A method for preparing a nicotine delivery product, said method comprising:

(a) mixing an aqueous solution of nicotine with a cation exchange resin, wherein the resin is polacrilex;

wherein the total amount of water is from 26 to 45% by weight of the total mixture;

(b) admixing with said complex of step (a) glycerol to form a mixture comprising a paste wherein the nicotine/cation exchange resin complex incorporates the glycerol; and

(c) removing water from said paste to produce said nicotine delivery product having a nicotine release rate of at least 80% over a 10 minute period.

13. The method of claim 1 , wherein the nicotine delivery product has a release rate that is higher than a nicotine delivery product made by first mixing glycerol with ion exchange resin and then admixing nicotine to the glycerol-ion exchange resin mixture.

14. A method for preparing a nicotine delivery product; said method comprising:

(a) mixing an aqueous suspension of a nicotine/cation exchange resin complex with an organic polyol or an aqueous solution or suspension thereof forming a mixture comprising a paste, wherein the total amount of water is from 26 to 45% by weight of the total mixture; wherein the resin is polacrilex; and

(b) removing water from the paste to produce said nicotine delivery product having a release rate of 80% or more over a 10 minute time period.