Compositions comprising a calcium channel blocker or a calmodulin blocker for use in the removal of hyperplastic skin lesions
View Patent ↗A composition, use of and a method of removing a hyperplastic skin lesion on a mammal comprising administering to the lesion or locus thereof a therapeutically effective amount of a composition comprising a blocker selected from the group consisting of a calcium channel blocker, a metabolite thereof, a calmodulin blocker and a metabolite thereof and a pharmaceutically acceptable diluent or carrier.
1. A method of removing an hyperplastic skin lesion
of the dermis and epidermis of a mammal, wherein said hyperplastic skin lesion is selected from the group consisting of calluses, corns, plantar warts, genital warts, cutaneous warts, and skin tags, comprising:
administering to said lesion or locus thereof a therapeutically effective amount of a composition comprising a blocker selected from the group consisting of a calcium channel blocker, a calmodulin blocker and a pharmaceutically acceptable diluent or carrier.
2. A method according to claim 1 , wherein said calcium channel blocker is verapamil.
3. A method according to claim 1 , wherein said calcium channel blocker is diltiazem.
4. A method according to claim 1 , wherein said calcium channel blocker is felodipine.
5. A method according to claim 1 , wherein said calmodulin blocker is trifluoperazine.
6. A method according to claim 1 , wherein said composition is in the form of a cream, spray, gel, ointment or patch.