IP Library Granted Patent US 9,023,092
Granted Patent B2
US 9,023,092 · App. 13/839,383 · Granted May 5, 2015

Endoscopes enhanced with pathogenic treatment

Inventors: Anthony Natale (New Preston, CT); David Muller (Boston, MA)
A61N5/062A61B1/018A61B1/015A61M5/00A61N5/0603A61B1/07A61B1/307A61B1/233A61B1/2676A61B1/317A61B1/3132A61B1/273A61B1/31A61N5/0624A61N2005/063A61N2005/0661A61B18/24A61B2018/00982
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Quick Facts
Patent No.
US 9,023,092
App. No.
13/839,383
Granted
May 5, 2015
Kind
B2
Abstract

Various endoscopes are integrated with an applicator configured for delivering a therapeutic solution to an internal anatomic target that may be infected by pathogenic microorganisms and a UV light-emitting device transmitting UV light thereto.

Claims (36)

1. A system for examining an internal anatomical target in a patient's body and treating pathogenic infections therein, the system comprising:

an endoscope comprising at least one optical channel for examining the internal anatomical target;

a device for delivering actinic radiation, the radiation-delivery device comprising a UV radiation source and an emission channel that is optically separate from the at least one optical channel;

an applicator comprising a reservoir for a radiation-activatable biocidal fluid having a riboflavin solution or a riboflavin-derivative solution and a fluidic channel; and

an inflatable balloon positioned proximal to an orifice of the applicator for localizing application of the radiation-activatable biocidal fluid;

wherein a light output of the emission channel and a fluidic outlet of the fluidic channel are configured for accessing the internal anatomical target and delivering actinic radiation and a radiation-activatable biocidal fluid, respectively, thereto without interfering with operation of the endoscope.

2. The system of claim 1 , wherein the endo scope, device and the applicator are integrated into a single assembly.

3. The system of claim 1 , wherein the endoscope is configured to enter a first surgical port and the light output and the fluidic outlet are configured to enter a second surgical port spaced apart from the first surgical port.

4. The system of claim 1 , wherein the endoscope is a gastrointestinal endoscope, comprising at least one working channel, the at least one optical channel guiding light to the internal anatomical target.

5. The system of claim 4 , wherein the working channel is the fluidic channel and the optical channel is the emission channel.

6. The system of claim 4 , wherein the emission channel and the fluidic channel are disposed within the working channel of the gastrointestinal endoscope.

7. The system of claim 1 , wherein the endoscope is a cystoscope, comprising a first channel for providing images of the internal anatomical target and a second channel for allowing fluids to be instilled into the internal anatomical target.

8. The system of claim 7 , wherein the first channel is the emission channel and the second channel is the fluidic channel.

9. The system of claim 7 , wherein the emission channel and the fluidic channel are inserted in the second channel of the cystoscope.

10. The system of claim 1 , wherein the endoscope is a nasopharyngoscope, the at least one optical channel guiding light to the internal anatomical target.

11. The system of claim 10 , further comprising a sleeve surrounding at least a portion of the nasopharyngoscope, wherein a channel created between the sleeve and an outer surface of the nasopharyngoscope is the fluidic channel and the optical channel is the emission channel.

12. The system of claim 10 , further comprising a sleeve surrounding at least a portion of the nasopharyngoscope, wherein a channel created between the sleeve and an outer surface of the nasopharyngoscope is the fluidic channel and the emission channel.

13. The system of claim 1 , wherein the endoscope is a bronchoscope, comprising at least one working channel.

14. The system of claim 13 , wherein the working channel is the fluidic channel and the optical channel is the emission channel.

15. The system of claim 13 , wherein the emission channel and the fluidic channel are inserted in the working channel of the bronchoscope.

16. The system of claim 1 , wherein the endoscope is an arthroscope, comprising a trocar having a lumen for guiding light to the internal anatomical target.

17. The system of claim 16 , wherein the emission channel and the fluidic channel are inserted in the lumen of the trocar.

18. The system of claim 16 , further comprising a sleeve surrounding at least a portion of the trocar, wherein a channel created between the sleeve and an outer surface of the arthroscope is the fluidic channel and the emission channel.

19. The system of claim 1 , wherein the endoscope is a laparoscope, comprising a trocar having an optical channel for guiding light to the internal anatomical target.

20. The system of claim 19 , further comprising a sleeve surrounding at least a portion of the trocar, wherein a channel created between the sleeve and an outer surface of the laparoscope is the fluidic channel and the optical channel is the emission channel.

21. The system of claim 19 , further comprising a sleeve surrounding at least a portion of the trocar, wherein a channel created between the sleeve and an outer surface of the laparoscope is the fluidic channel and the emission channel.

22. The system of claim 19 , wherein the emission channel and the fluidic channel are inserted in the optical channel of the trocar.

23. The system of claim 1 , further comprising a supply of the radiation-activatable biocidal fluid in the fluid reservoir for delivery to the internal anatomical target via the fluidic channel.

24. A method for examining an internal anatomical target in a patient's body and treating pathogenic infections therein, the method comprising:

inserting an endoscope comprising at least one optical channel adjacent to or into the internal anatomical target;

capturing an image of the target via the at least one optical channel of the endo scope;

while capturing the image and without interfering therewith, delivering a radiation-activatable biocidal fluid comprising a riboflavin solution or a riboflavin-derivative solution to the target;

inflating a balloon for localizing application of the radiation-activatable biocidal fluid; and

exposing the target to actinic radiation comprising a UV radiation via an emission channel to activate the radiation-activatable biocidal fluid, the emission channel being optically separate from the at least one optical channel.

25. The method of claim 24 , wherein the actinic radiation is UV radiation.

26. The method of claim 24 , wherein the radiation-activatable biocidal solution comprises a riboflavin solution or a riboflavin-derivative solution.

Continuity (3)
Continuation In Part 13592883 · Aug 23, 2012
Provisional Application 61526346 · Aug 23, 2011
Related Publication 20130274549A1 · Oct 17, 2013