Method of treating toxemia
A therapeutic agent for the treatment of toxemia, preeclampsia and eclampsia and a method for preparing the therapeutic agent are disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive/pancreatic enzymes. The therapeutic agent may be manufactured by a variety of encapsulation technologies. Delivery of the therapeutic agent may be made orally, through injection, by adherence of a medicated patch or by other methods. Further, a method of using the presence of chymotrypsin in the maternal GI tract as a biomarker, to determine the likelihood of developing preeclampsia, a pregnancy induced hypertension, and eclampsia/toxemia is disclosed.
1. A method for treating an individual exhibiting toxemia, the method comprising administering a therapeutically effective amount of a pharmaceutical preparation comprising digestive enzymes to the individual, wherein the digestive enzymes comprise an amylase, a lipase, a protease, or a combination thereof, whereby toxemia is treated.
2. The method of claim 1 , wherein the protease comprises chymotrypsin or trypsin.
3. The method of claim 1 , wherein the digestive enzymes are provided as pancreatin.
4. The method of claim 1 , wherein the digestive enzymes are obtained from a source selected from the group consisting of animal enzymes, plant enzymes, synthetic enzymes, and a combination thereof.
5. The method of claim 1 , wherein the pharmaceutical preparation is manufactured using a technology selected from the group consisting of enteric coating, lipid encapsulation, direct compression, dry granulation, wet granulation, and a combination thereof.
6. The method of claim 1 , wherein the pharmaceutical preparation is administered orally via a dosage formulation selected from the group consisting of: pills, tablets, capsules, microcapsules, mini-capsules, time released capsules, mini-tabs, sprinkles, and a combination thereof.
7. The method of claim 1 , wherein the amount of amylase ranges from 10,000 to 60,000 USP units/dose.
8. The method of claim 1 , wherein the amount of protease ranges from 10,000 to 70,000 USP units/dose.
9. The method of claim 1 , wherein the amount of lipase ranges from 4,000 to 30,000 USP units/dose.
10. The method of claim 3 , wherein the amount of pancreatin ranges from 2,000 to 6,000 USP units/dose.
11. The method of claim 2 , wherein the amount of chymotrypsin ranges from 2 to 5 mg/dose.
12. The method of claim 2 , wherein the amount of trypsin ranges from 60 to 100 mg/dose.