IP Library Granted Patent US 9,046,680
Granted Patent B2
US 9,046,680 · App. 12/399,823 · Granted Jun 2, 2015

Scanning illumination microscope

Inventors: Xiquan Cui (Pasadena, CA); Changhuei Yang (Pasadena, CA)
Assignee: California Institute of Technology
G02B21/0024G02B21/06G02B21/0032
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Quick Facts
Patent No.
US 9,046,680
App. No.
12/399,823
Granted
Jun 2, 2015
Kind
B2
Abstract

A microscopy method and configuration provides the ability to achieve wide field view and high resolution simultaneously. A beam array generator generates an M×N light beam array that illuminates a sample and an M×N sensor array. The sensor array obtains a whole microscopy image of the sample based on the light beam array. Each light beam of the array corresponds to one unique pixel sensor in the sensor array. A scanning of all light beams of the light beam array covers a whole area of the sample.

Claims (14)

1. A microscope comprising:

(a) a beam array generator configured to generate an M×N light beam array that illuminates a biological sample and an M×N sensor array; and

(b) the M×N sensor array configured to obtain a whole microscopy image of the biological sample based on the M×N light beam array, wherein:

(i) each light beam of the light beam array corresponds to one unique pixel sensor in the sensor array;

(ii) a scanning of all light beams of the light beam array covers a whole area of the biological sample;

(iii) the scanning comprises raster scanning; and

(iv) a scanning of each light beam of the light beam array covers a whole area of a corresponding pixel.

2. A method for obtaining a microscopy image of a biological sample comprising:

(a) generating, using a beam array generator, an M×N light beam array that illuminates the biological sample and an M×N sensor array; and

(b) obtaining, in the M×N sensor array, a whole microscopy image of the biological sample based on the M×N light beam array, wherein:

(i) each light beam of the light beam array corresponds to one unique pixel sensor in the sensor array;

(ii) a scanning of all light beams of the light beam array covers a whole area of the biological sample;

(iii) the scanning comprises raster scanning; and

(iv) a scanning of each light beam of the light beam array covers a whole area of a corresponding pixel.

Assignments (2)
CONFIRMATORY LICENSE Recorded Nov 23, 2011
From: CALIFORNIA INSTITUTE OF TECHNOLOGY
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 027281/0036 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2009
From: CUI, XIQUAN; YANG, CHANGHUEI
To: CALIFORNIA INSTITUTE OF TECHNOLOGY
Reel/Frame 022360/0588 →
Continuity (2)
Provisional Application 61068512 · Mar 7, 2008
Related Publication 20090225411A1 · Sep 10, 2009