IP Library Granted Patent US 9,051,351
Granted Patent B2
US 9,051,351 · App. 14/038,973 · Granted Jun 9, 2015

Hepatocyte growth factor mimics as therapeutic agents

Inventors: Joseph W. Harding (Pullman, WA); John W. Wright (Pullman, WA); Caroline C. Benoist (Nashville, TN); Leen H. Kawas (Pullman, WA); Gary A. Wayman (Pullman, WA)
Assignee: Washington State University
C07K5/06078C07K5/101C07K5/0808C07K14/4753A61K38/05
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Quick Facts
Patent No.
US 9,051,351
App. No.
14/038,973
Granted
Jun 9, 2015
Kind
B2
Abstract

Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia (e.g. Alzheimer's) and Parkinson's disease.

Claims (2)

1. A method for slowing progression of dementia associated with Alzheimer's disease or Parkinson's disease in a subject in need thereof comprising the step of

administering to said subject a therapeutic amount of hexanoic-tyrosine-isoleucine-(6)-amino-hexanoic amide.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 16, 2013
From: HARDING, JOSEPH W.; WRIGHT, JOHN W.; BENOIST, CAROLINE C.; KAWAS, LEEN H.; WAYMAN, GARY A.
To: WASHINGTON STATE UNIVERSITY
Reel/Frame 031785/0093 →
Continuity (6)
Continuation In Part PCTUS2012031815 · Apr 2, 2012
Provisional Application 61471122 · Apr 2, 2011
Provisional Application 61471124 · Apr 2, 2011
Provisional Application 61706567 · Sep 27, 2012
Provisional Application 61706437 · Sep 27, 2012
Related Publication 20140051633A1 · Feb 20, 2014