Granted Patent
B2
US 9,115,122 · App. 14/137,999 · Granted Aug 25, 2015
Non-ATP dependent inhibitors of extracellular signal-regulated kinase (ERK)
Inventors:
Paul S. Shapiro (Baltimore, MD); Alexander D. MacKerell, Jr. (Baltimore, MD); Steven Fletcher (Baltimore, MD)
Assignee:
UNIVERSITY OF MARYLAND, BALTIMORE
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Abstract
A compound, having the formula A-1: Wherein R 1 and R 2 are defined herein. Methods of using the compound and compositions containing the compound are provided.
Claims (6)
1. A compound, having the formula A-1:
wherein A-1 is one of the following compounds:
2. A composition, comprising the compound of claim 1 and a pharmaceutically acceptable carrier.
3. A compound, having the formula E-2:
wherein E-2 is one of the following compounds:
4. A composition, comprising the compound of claim 3 and a pharmaceutically acceptable carrier.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 7, 2014
From: SHAPIRO, PAUL S.; MACKERELL, ALEXANDER D., JR.; FLETCHER, STEVEN
To: UNIVERSITY OF MARYLAND, BALTIMORE
Reel/Frame 032167/0888 →
CONFIRMATORY LICENSE
Recorded Jan 9, 2014
From: THE UNIVERSITY OF MARYLAND, BALTIMORE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031924/0952 →
Continuity (3)
Provisional Application
61740156
· Dec 20, 2012
Provisional Application
61740172
· Dec 20, 2012