Optical scanning probe assembly
An optical scanning probe assembly for microscopic guide optic scanning and inspection of tissues includes an outer housing having a spring element for a scanning motor. The spring element is formed as a hollow tube configured to receive an optical guide, where the hollow tube has a mechanical stiffness larger than the optical guide to be received. The assembly further includes a lens system and a deflector configured to deflect the distal end of the hollow tube in directions transverse to the longitudinal extension of the hollow tube, so as to form an optical scan pattern.
1. An optical scanning probe assembly comprising:
a housing having a longitudinal axis;
a hollow tube centered on and extending lengthwise along the longitudinal axis inside the housing;
a holder for fixedly attaching a portion of the hollow tube to the housing;
a lens system provided inside the housing;
a mount having opposite proximal and distal ends, wherein
at the distal end, the mount is coupled to the lens system, and
at the proximal end, the mount is coupled to and surrounds a portion of the hollow tube; and
a scanning motor attached to and inside the housing at a certain distance from the mount for displacing the hollow tube transverse to the longitudinal axis to form an optical scan pattern.
2. The optical scanning probe assembly according to claim 1 , further comprising an optical guide for fitting inside the hollow tube.
3. The optical scanning probe assembly according to claim 2 , wherein the hollow rube serves as a spring element for the scanning motor, and wherein a mechanical stiffness of the hollow tube is larger than a mechanical stiffness of the optical guide.
4. The optical scanning probe assembly according to claim 3 , wherein a result of division of the mechanical stiffness of the hollow tube by the mechanical stiffness of the optical guide is greater than at least one of 1.05 and 1.5.
5. The optical scanning probe assembly according to claim 3 , wherein a result of division of the mechanical stiffness of the hollow tube by the mechanical stiffness of the optical guide is greater than at least one of 2 and 5.
6. The optical scanning probe assembly according to claim 3 , wherein a result of division of the mechanical stiffness of the hollow tube by the mechanical stiffness of the optical guide is greater than 10.
7. The optical scanning probe assembly of claim 3 , wherein the hollow tube has an outer diameter of about 0.8 mm and an inner diameter of about 0.5 mm.
8. The optical scanning probe assembly of claim 2 , wherein the optical guide comprises an optical fiber.
9. The optical scanning probe assembly according to c an wherein the lens system is centered on the longitudinal axis.
10. The optical scanning probe assembly according to claim 1 , wherein the housing forms a part of any of an endoscope, a catheter, a needle, or a biopsy needle.
11. The optical scanning probe assembly according to claim 2 , further comprising an optical window at the distal end, wherein the mount positions the optical guide at a first distance away from the lens system, and the scanning motor is configured to adjust a position of the mount to form a focal point t outside the outer housing at a distance in a range selected from one of 5 μm to 1000 μm, 10 μm to 500 μm, and 10 μm to 200 μm from the optical window.
12. The optical scanning probe assembly according to claim 11 , wherein the optical guide is positioned at a second distance extending beyond the hollow tube within the mount, and wherein the second distance is one of larger than 5 micron, and larger than 10 micron.
13. An optical imaging system comprising:
an optical scanning probe assembly including:
a housing having a longitudinal axis,
a hollow tube centered on and extending lengthwise along the longitudinal axis inside the housing,
a holder for fixedly attaching a portion of the hollow tube to the housing,
a lens system provided inside the housing,
a mount having opposite proximal and distal ends, wherein
at the distal end, the mount is coupled to the lens system, and
at the proximal end, the mount is coupled to and surrounds a portion of the hollow tube, and
a scanning motor attached to and inside the housing at a certain distance from the mount for displacing the hollow tube transverse to the longitudinal axis to form an optical scan pattern;
a scanning unit operationally connected to the scanning motor for controlling the scanning motor to form the optical scan pattern;
a radiation source for providing radiation guided by an optical guide held in the hollow tube; and
an imaging detector being arranged for imaging using reflected or emitted radiation from a region of interest.
14. A method for optical scanning imaging, the method comprising the acts of:
providing an optical scanning probe assembly including:
a housing having a longitudinal axis;
a hollow tube centered on and extending lengthwise along the longitudinal axis inside the housing,
a holder for fixedly attaching a portion of the hollow tube to the housing,
an optical guide inserted into the hollow tube,
a lens system provided inside the housing,
a mount having opposite proximal and distal ends, wherein
at the distal end, the mount is coupled to the lens system, and
at the proximal end, the mount is coupled to and surrounds a portion of the hollow tube, and
a scanning motor attached to and inside the housing at a certain distance from the mount for displacing the hollow tube transverse to the longitudinal axis to form an optical scan pattern;
arranging the optical scanning probe assembly in relation to an optical radiation source to guide radiation from the radiation source through the optical guide; and
adjusting a position of the optical guide in a direction along and transverse to the longitudinal axis to control a position of an image of the guided radiation formed by the lens system.