Reduction of concomitant infections in pigs by the use of PCV2 antigen
The present invention relates to a method for reducing the percentage of concomitant infections in pigs or a herd of pigs caused by pathogens other than PCV2 comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen. It also refers to a method for improving the resistance of pigs against concomitant infections with pathogens other than PCV2, comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen.
1. A method for reducing the percentage of concomitant infections in pigs or a herd of pigs caused by one or more pathogens other than PCV2 comprising the step administering to said pig(s) a single dose of an immunogenic composition comprising 4-400 μg of PCV2 ORF2 antigen and at least one further component selected from the group consisting of inactivated viral vector, cell culture supernate, media, viral inactivators, neutralization agents for viral inactivators, antibiotics, and combinations thereof, wherein the number of pigs infected with one or more of the pathogens other than PCV2 is reduced with regard to one or more of the pathogens by more than 10% after a single dose of the immunogenic composition comprising PCV2 ORF2 when compared to those pigs not receiving the PCV2 ORF2 composition, and wherein the concomitant infections are selected from the group of consisting of Actinobacillus pleuropneumoniae, Haemophilus parasuis, Mycoplasma hyrhinis, Mycoplasma hyopneumoniae, Pasteurella multocida, Salmonella spp., Strepococcus suis , porcine reproductive and respiratory syndrome virus (PRRSV), and combinations thereof.
2. The method according to claim 1 , characterized in that the pigs or the herd of pigs are/is infected with PCV2.
3. A method for improving the resistance of pigs against concomitant infections with one or more pathogens other than PCV2, comprising the step administering to said pig(s) a single dose of an immunogenic composition comprising 4-400 μg of PCV2 ORF2 antigen and at least one further component selected from the group consisting of inactivated viral vector, cell culture supernate, media, viral inactivators, neutralization agents for viral inactivators, antibiotics, and combinations thereof, wherein the number of pigs infected with one or more of the pathogens other than PCV2 is reduced with regard to one of more of the pathogens by more than 10% after a single dose of the immunogenic composition comprising PCV2 ORF2 when compared to those pigs not receiving the PCV2 ORF2 composition, and wherein the concomitant infections are selected from the group consisting of Actinobacillus pleuropneumoniae, Haemophilus parasuis, Mycoplasma hyrhinis, Mycoplasma hyopneumoniae, Pasteurella multocida, Salmonella spp., Strepococcus suis , porcine reproductive and respiratory syndrome virus (PRRSV), and combinations thereof.
4. The method according to claim 3 , characterized in that the pigs are infected with PCV2.