Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field
The present invention relates to compounds comprising the general formula (I), in which R 1 and R 2 , which may be identical or different, are selected from the group comprising —H or a linear or branched alkyl group having from 1 to 6 carbon atoms or together form an aromatic or aliphatic ring with 5 or 6 atoms, Y and Z, which may be identical or different, are selected from the group comprising —H, OH, —COOH, —OR 3 , —CH(OR 3 )COOH, in which R 3 is selected from H, phenyl, benzyl, CF, or CF 3 or CF 2 CF 3 , vinyl, allyl and a linear or branched alkyl group having from 1 to 6 carbon atoms.
1. A method of treating Crohn's disease in a mammal in need thereof, comprising administering to said mammal a compound represented by:
or salts thereof.
2. The method of claim 1 , wherein the compound is in an enantiomerically pure R or S form.
3. A pharmaceutical composition comprising 3-(4′-aminophenyl)2-methoxypropionic acid (compound 34), or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable excipient.