Granted Patent
B2
US 9,138,484 · App. 12/666,712 · Granted Sep 22, 2015
Conjugates containing hydrophilic spacer linkers
Inventors:
Christopher Paul Leamon (West Lafayette, IN); Iontcho Radoslavov Vlahov (West Lafayette, IN); Hari Krishna R. Santhapuram (West Lafayette, IN); Paul Joseph Kleindl (Lebanon, IN); Yu Wang (Fishers, IN); Fei You (West Lafayette, IN)
Assignee:
Endocyte, Inc.
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Abstract
Described herein are compositions and methods for use in targeted drug delivery using cell receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in imaging, diagnosing, and/or treating diseases and disease states caused by pathogenic cell populations.
Claims (3)
1. A compound of the formula
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a therapeutically effective amount of the compound of claim 1 , or a pharmaceutically acceptable salt thereof, and optionally a diluent, carrier, or excipient therefor, or combination thereof.
Continuity (3)
Provisional Application
60946092
· Jun 25, 2007
Provisional Application
61036186
· Mar 13, 2008