IP Library Granted Patent US 9,138,484
Granted Patent B2
US 9,138,484 · App. 12/666,712 · Granted Sep 22, 2015

Conjugates containing hydrophilic spacer linkers

Inventors: Christopher Paul Leamon (West Lafayette, IN); Iontcho Radoslavov Vlahov (West Lafayette, IN); Hari Krishna R. Santhapuram (West Lafayette, IN); Paul Joseph Kleindl (Lebanon, IN); Yu Wang (Fishers, IN); Fei You (West Lafayette, IN)
Assignee: Endocyte, Inc.
A61K47/4813A61K47/48215A61K47/48338
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Quick Facts
Patent No.
US 9,138,484
App. No.
12/666,712
Granted
Sep 22, 2015
Kind
B2
Abstract

Described herein are compositions and methods for use in targeted drug delivery using cell receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in imaging, diagnosing, and/or treating diseases and disease states caused by pathogenic cell populations.

Claims (3)

1. A compound of the formula

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a therapeutically effective amount of the compound of claim 1 , or a pharmaceutically acceptable salt thereof, and optionally a diluent, carrier, or excipient therefor, or combination thereof.

Continuity (3)
Provisional Application 60946092 · Jun 25, 2007
Provisional Application 61036186 · Mar 13, 2008
Related Publication 20100323973A1 · Dec 23, 2010