Granted Patent
B2
US 9,149,489 · App. 12/920,104 · Granted Oct 6, 2015
Inhibitors of glycolysis useful in the treatment of brain tumors
Inventors:
Waldeman Priebe (Houston, TX); Charles Conrad (Spring, TX); Timothy Madden (Sugar Land, TX); Izabela Fokt (Houston, TX); Slawomir Szymanski (Spring, TX); Leposava Antonovic (Houston, TX)
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Abstract
Provided herein are methods of treating brain tumors by administering a therapeutically effective amount of a compound of the Formulas I or II to a patient in need thereof.
Claims (1)
1. A method of treating highly glycolytic brain tumors comprising administering to a subject in need thereof a therapeutically effective amount of 2-Deoxy-2,2-difluoro-D-arabino-hexopyranose.
Assignments (2)
CONFIRMATORY LICENSE
Recorded Jan 29, 2018
From: UNIVERSITY OF TX MD ANDERSON CAN CTR
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 045171/0572 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 9, 2010
From: PRIEBE, WALDEMAR; FOKT, IZABELA; SZYMANSKI, SLAWOMIR; ANTONOVIC, LEPOSAVA; CONRAD, CHARLES; MADDEN, TIMOTHY
To: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 024959/0827 →
Continuity (5)
Continuation In Part
12280322
Provisional Application
61032796
· Feb 29, 2008
Provisional Application
60796173
· Apr 28, 2006
Provisional Application
60795621
· Apr 27, 2006