IP Library Granted Patent US 9,149,501
Granted Patent B2
US 9,149,501 · App. 13/937,999 · Granted Oct 6, 2015

Methods of treating depression and other related diseases

Inventor: Joseph Moskal (Evanston, IL)
Assignee: Northwestern University
A61K38/07A61K45/06C07K5/06139C07K5/081C07K5/0821C07K5/1013
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,149,501
App. No.
13/937,999
Granted
Oct 6, 2015
Kind
B2
Abstract

The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.

Claims (14)

1. A method for treating psychotic depression in a patient in need thereof, comprising administering to said patient a 1 mg/kg to about 10 mg/kg dose of a compound represented by:

or pharmaceutically acceptable salts, thereof.

2. The method of claim 1 , comprising administering the dose every week or every two weeks to said patient.

3. The method of claim 1 , wherein administration of a single dose is effective for up to 4 days.

4. The method of claim 1 , further comprising administering another antidepressant drug.

5. The method of claim 2 , further comprising administering another antidepressant drug.

6. A method for treating a psychotic depression comprising administering, every week or every two weeks to a patient in need thereof, a pharmaceutically acceptable composition comprising:

about 1 mg/kg to about 10 mg/kg dose of a compound represented by:

or pharmaceutically acceptable salts thereof; and

an excipient.

7. A method for treating a psychotic depression in a patient in need thereof, comprising administering to said patient a dose of about 1 mg/kg to about 10 mg/kg of a compound represented by:

or pharmaceutically acceptable salts thereof.

8. The method of claim 7 , comprising administering the dose every week or every two weeks to said patient.

9. The method of claim 7 , wherein administration of a single dose is effective for up to 4 days.

Assignments (3)
SECURITY INTEREST Recorded Dec 18, 2024
From: GATE NEUROSCIENCES, INC.
To: INNOVIVA TRC HOLDINGS LLC
Reel/Frame 069742/0846 →
SECURITY INTEREST Recorded Nov 6, 2023
From: GATE NEUROSCIENCES, INC.
To: INNOVIVA TRC HOLDINGS LLC
Reel/Frame 065473/0327 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2013
From: MOSKAL, JOSEPH
To: NORTHWESTERN UNIVERSITY
Reel/Frame 031062/0182 →
Continuity (8)
Continuation 13909712 · Jun 4, 2013
Continuation 13608556 · Sep 10, 2012
Continuation 13440368 · Apr 5, 2012
Continuation In Part PCTUS2010051415 · Oct 5, 2010
Provisional Application 61248650 · Oct 5, 2009
Provisional Application 61471942 · Apr 5, 2011
Provisional Application 61507252 · Jul 13, 2011
Related Publication 20130316954A1 · Nov 28, 2013