IP Library Granted Patent US 9,169,211
Granted Patent B2
US 9,169,211 · App. 14/510,652 · Granted Oct 27, 2015

8-hydroxy quinoline derivatives

Inventors: Kevin Jeffrey Barnham (Coburg, AU); Elisabeth Colette Louise Gautier (Bentleigh, AU); Gaik Beng Kok (North Carlton, AU); Guy Krippner (Glen Waverley, AU)
Assignee: PRANA BIOTECHNOLOGY LIMITED
C07D215/48A61K31/47A61K31/4709A61K31/4725A61K45/06C07D215/00C07D215/24C07D215/26C07D215/28C07D215/38C07D401/04C07D401/12C07D401/14C07D409/04C07D417/12C07D417/14
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Quick Facts
Patent No.
US 9,169,211
App. No.
14/510,652
Granted
Oct 27, 2015
Kind
B2
Abstract

The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.

Claims (5)

1. A method for the treatment of Huntington's disease in a subject in need thereof which comprises administering to the subject a therapeutically effective amount of a compound of the formula

or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , in which the compound is administered in association with a pharmaceutically acceptable carrier.

3. The method of claim 1 , in which the compound is administered in association with a medicament, said medicament being an inhibitor of the acetyl cholinesterase active site, an antioxidant, an anti-inflammatory agent or an oestrogenic agent.

4. The method of claim 1 , in which the compound is in hydrate form.

Priority Claims (1)
AU 2002950217 · Jul 16, 2002 · national
Continuity (3)
Continuation 11901941 · Sep 19, 2007
Continuation In Part 10521902
Related Publication 20150094334A1 · Apr 2, 2015